Brown adipose tissue (BAT) displays the unique capacity to generate heat through
uncoupled oxidative phosphorylation that makes it a very attractive therapeutic target for …

Cardiac natriuretic peptides (NPs), atrial NP (ANP) and B-type NP (BNP) are true hormones
produced and released by cardiomyocytes, exerting several systemic effects. Together with …

Brown adipose tissue (BAT) and beige adipose tissue combust fuels for heat production in
adult humans, and so constitute an appealing target for the treatment of metabolic disorders …

Brown adipose tissue (BAT) combusts high amounts of fatty acids, thereby lowering plasma
triglyceride levels and reducing obesity. However, the precise role of BAT in plasma …

Thermogenic adipocytes possess a therapeutically appealing, energy-expending capacity,
which is canonically cold-induced by ligand-dependent activation of β-adrenergic G protein …

Triglyceride-rich lipoproteins deliver fatty acids to tissues for oxidation and for storage.
Release of fatty acids from circulating lipoprotein triglycerides is carried out by lipoprotein …

The coordination of the organ-specific responses regulating systemic energy distribution to
replenish lipid stores in acutely activated brown adipose tissue (BAT) remains elusive. Here …

Atherosclerosis, for which hyperlipidemia is a major risk factor, is the leading cause of
morbidity and mortality in Western society, and new therapeutic strategies are highly …

In rodents, brown adipose tissue (BAT) plays an important role in producing heat to defend
against the cold and can metabolize large amounts of dietary fatty acids (DFA). The role of …

Brown and beige adipocytes combust nutrients for thermogenesis and through their
metabolic activity decrease pro-atherogenic remnant lipoproteins in hyperlipidemic mice …