Pathogenic mechanisms of post-acute sequelae of SARS-CoV-2 infection (PASC)

ZA Sherif, CR Gomez, TJ Connors, TJ Henrich… - Elife, 2023 - elifesciences.org
COVID-19, with persistent and new onset of symptoms such as fatigue, post-exertional
malaise, and cognitive dysfunction that last for months and impact everyday functioning, is …

Long covid—mechanisms, risk factors, and management

H Crook, S Raza, J Nowell, M Young, P Edison - bmj, 2021 - bmj.com
Since its emergence in Wuhan, China, covid-19 has spread and had a profound effect on
the lives and health of people around the globe. As of 4 July 2021, more than 183 million …

An update on drugs with therapeutic potential for SARS-CoV-2 (COVID-19) treatment

S Drożdżal, J Rosik, K Lechowicz, F Machaj… - Drug Resistance …, 2021 - Elsevier
The COVID-19 pandemic is one of the greatest threats to human health in the 21st century
with more than 257 million cases and over 5.17 million deaths reported worldwide (as of …

[HTML][HTML] Post-acute COVID-19 syndrome

A Nalbandian, K Sehgal, A Gupta, MV Madhavan… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …

Long-COVID and post-COVID health complications: an up-to-date review on clinical conditions and their possible molecular mechanisms

B Silva Andrade, S Siqueira, WR de Assis Soares… - Viruses, 2021 - mdpi.com
The COVID-19 pandemic has infected millions worldwide, leaving a global burden for long-
term care of COVID-19 survivors. It is thus imperative to study post-COVID (ie, short-term) …

Virology, transmission, and pathogenesis of SARS-CoV-2

M Cevik, K Kuppalli, J Kindrachuk, M Peiris - bmj, 2020 - bmj.com
• In the respiratory tract, peak SARS-CoV-2 load is observed at the time of symptom onset or
in the first week of illness, with subsequent decline thereafter, indicating the highest …

Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance

T Kotecha, DS Knight, Y Razvi, K Kumar… - European heart …, 2021 - academic.oup.com
Background Troponin elevation is common in hospitalized COVID-19 patients, but
underlying aetiologies are ill-defined. We used multi-parametric cardiovascular magnetic …

Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages

M Merad, JC Martin - Nature reviews immunology, 2020 - nature.com
The COVID-19 pandemic caused by infection with SARS-CoV-2 has led to more than
200,000 deaths worldwide. Several studies have now established that the …

[HTML][HTML] Hyperinflammatory shock in children during COVID-19 pandemic

S Riphagen, X Gomez, C Gonzalez-Martinez… - The Lancet, 2020 - thelancet.com
South Thames Retrieval Service in London, UK, provides paediatric intensive care support
and retrieval to 2 million children in South East England. During a period of 10 days in mid …

Covid‐19 and kidney injury: Pathophysiology and molecular mechanisms

E Ahmadian, SM Hosseiniyan Khatibi… - Reviews in medical …, 2021 - Wiley Online Library
The novel coronavirus (SARS‐CoV‐2) has turned into a life‐threatening pandemic disease
(Covid‐19). About 5% of patients with Covid‐19 have severe symptoms including septic …