The microbial ecology of Escherichia coli in the vertebrate gut

E Foster-Nyarko, MJ Pallen - FEMS microbiology reviews, 2022 - academic.oup.com
Escherichia coli has a rich history as biology's 'rock star', driving advances across many
fields. In the wild, E. coli resides innocuously in the gut of humans and animals but is also a …

Plant pangenomics: approaches, applications and advancements

MF Danilevicz, CGT Fernandez, JI Marsh… - Current opinion in plant …, 2020 - Elsevier
Highlights•Pan-genomes represent the complex genomic diversity found in plant
species.•Novel approaches are under development to enable more complex pan-genome …

[HTML][HTML] Hospital admission and emergency care attendance risk for SARS-CoV-2 delta (B. 1.617. 2) compared with alpha (B. 1.1. 7) variants of concern: a cohort …

KA Twohig, T Nyberg, A Zaidi, S Thelwall… - The Lancet Infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant was first detected in
England in March, 2021. It has since rapidly become the predominant lineage, owing to high …

[HTML][HTML] Evaluating the effects of SARS-CoV-2 spike mutation D614G on transmissibility and pathogenicity

E Volz, V Hill, JT McCrone, A Price, D Jorgensen… - Cell, 2021 - cell.com
Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G
are suggestive of a selective advantage but may also be due to a random founder effect. We …

[HTML][HTML] Characterization of antimicrobial-resistant Gram-negative bacteria that cause neonatal sepsis in seven low-and middle-income countries

K Sands, MJ Carvalho, E Portal, K Thomson… - Nature …, 2021 - nature.com
Antimicrobial resistance in neonatal sepsis is rising, yet mechanisms of resistance that often
spread between species via mobile genetic elements, ultimately limiting treatments in low …

[HTML][HTML] A large-scale genomic snapshot of Klebsiella spp. isolates in Northern Italy reveals limited transmission between clinical and non-clinical settings

HA Thorpe, R Booton, T Kallonen, MJ Gibbon… - Nature …, 2022 - nature.com
The Klebsiella group, found in humans, livestock, plants, soil, water and wild animals, is
genetically and ecologically diverse. Many species are opportunistic pathogens and can …

Multiplex PCR method for MinION and Illumina sequencing of Zika and other virus genomes directly from clinical samples

J Quick, ND Grubaugh, ST Pullan, IM Claro, AD Smith… - Nature protocols, 2017 - nature.com
Genome sequencing has become a powerful tool for studying emerging infectious diseases;
however, genome sequencing directly from clinical samples (ie, without isolation and …

[HTML][HTML] Changing composition of SARS-CoV-2 lineages and rise of Delta variant in England

S Mishra, S Mindermann, M Sharma, C Whittaker… - …, 2021 - thelancet.com
Background Since its emergence in Autumn 2020, the SARS-CoV-2 Variant of Concern
(VOC) B. 1.1. 7 (WHO label Alpha) rapidly became the dominant lineage across much of …

ARIBA: rapid antimicrobial resistance genotyping directly from sequencing reads

M Hunt, AE Mather, L Sánchez-Busó… - Microbial …, 2017 - microbiologyresearch.org
Antimicrobial resistance (AMR) is one of the major threats to human and animal health
worldwide, yet few high-throughput tools exist to analyse and predict the resistance of a …

[HTML][HTML] An integrated national scale SARS-CoV-2 genomic surveillance network

T COVID - The Lancet. Microbe, 2020 - ncbi.nlm.nih.gov
The Coronavirus Disease 2019 (COVID-19) Genomics UK Consortium (COG-UK) was
launched in March, 2020, with£ 20 million support from UK Research and Innovation, the UK …