The rapid generation of molecular complexity from simple starting materials is of paramount
importance in synthetic chemistry. The unique combination of high reactivity and high …

First-row transition-metal-mediated reactions constitute an important and growing area of
research due to the low cost, low toxicity, and exceptional synthetic versatility of these …

Few methods permit the hydrogenation of alkenes to a thermodynamically favored
configuration when steric effects dictate the alternative trajectory of hydrogen delivery …

Biosynthesis via carbocations: Theoretical studies on terpene formation - Natural Product Reports
(RSC Publishing) DOI:10.1039/C1NP00006C Royal Society of Chemistry View PDF …

New catalytic strategies that leverage single-electron redox events have provided chemists
with useful tools for solving synthetic problems. In this context, Ti offers opportunities that are …

From its humble origins as a mere 'chemical curiosity,'radical chemistry has developed into
one of the most powerful tools for preparative organic synthesis. Initially considered too …

The power of cation-initiated cyclizations of polyenes for the synthesis of polycyclic
terpenoids cannot be overstated. However, a major limitation is the intolerance of many …

The reactivity of water with both carbanion and carbocation intermediates is well known, but
until now it has generally been believed that water is inert towards free radicals.[1] This …

Transition‐metal‐catalyzed radical reactions are becoming increasingly important in modern
organic chemistry. They offer fascinating and unconventional ways for connecting molecular …

Indolosesquiterpenoids are a growing class of natural products that exhibit a wide range of
biological activities. Here, we report the total syntheses of xiamycin A and oridamycins A and …