Antibiotics from Gram-negative bacteria: a comprehensive overview and selected biosynthetic highlights

J Masschelein, M Jenner, GL Challis - Natural product reports, 2017 - pubs.rsc.org
Covering: up to 2017 The overwhelming majority of antibiotics in clinical use originate from
Gram-positive Actinobacteria. In recent years, however, Gram-negative bacteria have …

[HTML][HTML] Microbial bioformulation: a microbial assisted biostimulating fertilization technique for sustainable agriculture

A Khan, AV Singh, SS Gautam, A Agarwal… - Frontiers in Plant …, 2023 - frontiersin.org
Addressing the pressing issues of increased food demand, declining crop productivity under
varying agroclimatic conditions, and the deteriorating soil health resulting from the overuse …

Promoter Activation in Δhfq Mutants as an Efficient Tool for Specialized Metabolite Production Enabling Direct Bioactivity Testing

E Bode, AK Heinrich, M Hirschmann… - Angewandte …, 2019 - Wiley Online Library
Natural products (NPs) from microorganisms have been important sources for discovering
new therapeutic and chemical entities. While their corresponding biosynthetic gene clusters …

[HTML][HTML] The importance of antimicrobial compounds produced by beneficial bacteria on the biocontrol of phytopathogens

C Cesa-Luna, A Baez, V Quintero-Hernández… - Acta biológica …, 2020 - scielo.org.co
Bacteria produce antimicrobial compounds to compete for nutrients and space in a particular
habitat. Antagonistic interactions can be evaluated by several methodologies including the …

An auxin controls bacterial antibiotics production

MA Matilla, A Daddaoua, A Chini, B Morel… - Nucleic Acids …, 2018 - academic.oup.com
The majority of clinically used antibiotics originate from bacteria. As the need for new
antibiotics grows, large-scale genome sequencing and mining approaches are being used …

[HTML][HTML] Improved production of andrimid in Erwinia persicina BST187 strain by fermentation optimization

T Cheng, T Ge, L Zhao, Y Hou, J Xia, L Zhao - BMC microbiology, 2023 - Springer
Background Andrimid is reported to be a novel kind of polyketide-nonribosomal peptide
hybrid product (PK-NRPs) that inhibits fatty acid biosynthesis in bacteria. Considering its …

Dynamics of marine bacterial biofouling communities after initial Alteromonas genovensis biofilm attachment to anti-fouling paint substrates

HJ Kim, JS Park, TK Lee, D Kang, JH Kang, K Shin… - Marine Pollution …, 2021 - Elsevier
To determine how bacterial communities succeed after the initial attachment of the bacterial
biofilm adhesion using 16S rDNA meta-barcoding in plates coated with copper-based anti …

Regulation of indole‐3‐acetic acid biosynthesis and consequences of auxin production deficiency in Serratia plymuthica

M Rico‐Jiménez, S Muñoz‐Mira… - Microbial …, 2023 - Wiley Online Library
Abstract Indole‐3‐acetic acid (IAA) is emerging as a key intra‐and inter‐kingdom signal
molecule that modulates a wide range of processes of importance during plant …

[HTML][HTML] The integration of genome mining, comparative genomics, and functional genetics for biosynthetic gene cluster identification

AN Williams, N Sorout, AJ Cameron… - Frontiers in …, 2020 - frontiersin.org
Antimicrobial resistance is a worldwide health crisis for which new antibiotics are needed.
One strategy for antibiotic discovery is identifying unique antibiotic biosynthetic gene …

LysR-type transcriptional regulators: state of the art

S Mayo-Pérez, Y Gama-Martínez, S Dávila… - Critical Reviews in …, 2023 - Taylor & Francis
The LysR-type transcriptional regulators (LTTRs) are DNA-binding proteins present in
bacteria, archaea, and in algae. Knowledge about their distribution, abundance, evolution …