Elastin‐like polypeptides (ELPs) are thermally responsive biopolymers that consist of a
repeated amino acid motif derived from human tropoelastin. These peptides exhibit …

Hybrid or recombinant protein-polymers, peptide-based biomaterials, and antibody-targeted
therapeutics are widely explored for various ocular conditions and vision correction. They …

Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …

Dry eye disease (DED) is associated with ocular hyperosmolarity and inflammation. The
marketed topical eye drops for DED treatment often lack bioavailability and precorneal …

Proteins implement many useful functions, including binding ligands with unparalleled
affinity and specificity, catalyzing stereospecific chemical reactions, and directing cell …

Elastin-like polypeptides (ELPs) are thermally responsive biopolymers derived from natural
elastin. These peptides have a low critical solution temperature phase behavior and can be …

The separation and purification of therapeutic proteins from their biological resources pose a
great limitation for industrial manufacturing of biologics in an efficient and cost-effective …

Although polyethylene glycol (PEG), or “PEGylation” has become a widely applied approach
for improving the efficiency of drug delivery, the immunogenicity and non-biodegradability of …

Elastin-like polypeptides (ELPs) are bioengineered proteins that have a unique physical
property, a thermally triggered inverse phase transition, that can be exploited for drug …

Protein‐polymer conjugates show improved pharmacokinetics but reduced bioactivity and
tumor penetration as compared to native proteins, resulting in limited antitumor efficacy. To …