Hyaluronic acid: A review on its biology, aspects of drug delivery, route of administrations and a special emphasis on its approved marketed products and recent …
Hyaluronic acid (HA) is a large non-sulphated glycosaminoglycan that is an important
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …
component of extracellular matrix (ECM) and a biodegradable polymer. Due to a variation in …
[HTML][HTML] Hyaluronan, a crucial regulator of inflammation
AC Petrey, CA de la Motte - Frontiers in immunology, 2014 - frontiersin.org
Hyaluronan (HA), a major component of the extracellular matrix (ECM), plays a key role in
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …
regulating inflammation. Inflammation is associated with accumulation and turnover of HA …
Hyaluronan as an immune regulator in human diseases
Accumulation and turnover of extracellular matrix components are the hallmarks of tissue
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …
injury. Fragmented hyaluronan stimulates the expression of inflammatory genes by a variety …
Biomaterials for cell transplantation
N Mitrousis, A Fokina, MS Shoichet - Nature Reviews Materials, 2018 - nature.com
Cell transplantation holds immense potential for reversing diseases that are currently
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …
incurable and for regenerating tissues. However, poor cell survival, cell aggregation and …
Hyaluronan: biosynthesis and signaling
Background Hyaluronan is a critical component of extracellular matrix with several different
roles. Besides the contribution to the tissue hydration, mechanical properties and correct …
roles. Besides the contribution to the tissue hydration, mechanical properties and correct …
[HTML][HTML] 4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer
Hyaluronan (HA) is a prominent component of the extracellular matrix at many sites of
chronic inflammation, including type 1 diabetes (T1D), multiple sclerosis, and numerous …
chronic inflammation, including type 1 diabetes (T1D), multiple sclerosis, and numerous …
Endogenous toll‐like receptor ligands and their biological significance
L Yu, L Wang, S Chen - Journal of cellular and molecular …, 2010 - Wiley Online Library
Introduction• TLR signalling• Endogenous TLR ligands• Biological significance of signalling
triggered by endogenous TLR ligands‐Ischemia and reperfusion injury‐Tissue repair and …
triggered by endogenous TLR ligands‐Ischemia and reperfusion injury‐Tissue repair and …
Hyaluronan in tissue injury and repair
A hallmark of tissue injury and repair is the turnover of extracellular matrix components. This
review focuses on the role of the glycosaminoglycan hyaluronan in tissue injury and repair …
review focuses on the role of the glycosaminoglycan hyaluronan in tissue injury and repair …
The role of biomaterials and scaffolds in immune responses in regenerative medicine: macrophage phenotype modulation by biomaterial properties and scaffold …
Scaffolds are an integral part of the regenerative medicine field. The contact of biomaterials
with tissue, as was clearly observed over the years, induces immune reactions in a material …
with tissue, as was clearly observed over the years, induces immune reactions in a material …