The potential role of RNA N6-methyladenosine in Cancer progression
T Wang, S Kong, M Tao, S Ju - Molecular cancer, 2020 - Springer
Abstract N6-methyladenosine (m6A) is considered the most common, abundant, and
conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA) …
conserved internal transcript modification, especially in eukaryotic messenger RNA (mRNA) …
Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA
P Wu, Y Mo, M Peng, T Tang, Y Zhong, X Deng… - Molecular cancer, 2020 - Springer
Non-coding RNAs do not encode proteins and regulate various oncological processes. They
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …
are also important potential cancer diagnostic and prognostic biomarkers. Bioinformatics …
[HTML][HTML] Lactylation-driven METTL3-mediated RNA m6A modification promotes immunosuppression of tumor-infiltrating myeloid cells
J Xiong, J He, J Zhu, J Pan, W Liao, H Ye, H Wang… - Molecular cell, 2022 - cell.com
Tumor-infiltrating myeloid cells (TIMs) are crucial cell populations involved in tumor immune
escape, and their functions are regulated by multiple epigenetic mechanisms. The precise …
escape, and their functions are regulated by multiple epigenetic mechanisms. The precise …
Exon architecture controls mRNA m6A suppression and gene expression
N 6-methyladenosine (m6A) is the most abundant messenger RNA (mRNA) modification
and plays crucial roles in diverse physiological processes. Using a massively parallel assay …
and plays crucial roles in diverse physiological processes. Using a massively parallel assay …
METTL3/IGF2BP3 axis inhibits tumor immune surveillance by upregulating N6-methyladenosine modification of PD-L1 mRNA in breast cancer
W Wan, X Ao, Q Chen, Y Yu, L Ao, W Xing, W Guo… - Molecular cancer, 2022 - Springer
Background Continual expression of PD-L1 in tumor cells is critical for tumor immune
escape and host T cell exhaustion, however, knowledge on its clinical benefits through …
escape and host T cell exhaustion, however, knowledge on its clinical benefits through …
YTHDF2 mediates the mRNA degradation of the tumor suppressors to induce AKT phosphorylation in N6-methyladenosine-dependent way in prostate cancer
Abstract Background N6-methyladenosine (m 6 A) is the most abundant modification in
mRNA of humans. Emerging evidence has supported the fact that m 6 A is comprehensively …
mRNA of humans. Emerging evidence has supported the fact that m 6 A is comprehensively …
m6A-Atlas: a comprehensive knowledgebase for unraveling the N6-methyladenosine (m6A) epitranscriptome
Abstract N 6-Methyladenosine (m6A) is the most prevalent RNA modification on mRNAs and
lncRNAs. It plays a pivotal role during various biological processes and disease …
lncRNAs. It plays a pivotal role during various biological processes and disease …
N6-Methyladenosine-modified circSAV1 triggers ferroptosis in COPD through recruiting YTHDF1 to facilitate the translation of IREB2
H Xia, Y Wu, J Zhao, C Cheng, J Lin, Y Yang… - Cell Death & …, 2023 - nature.com
Epithelial cell damage-initiated chronic obstructive pulmonary disease (COPD) is implicated
in regulated cell death (RCD) including ferroptosis triggered by complex gene-environment …
in regulated cell death (RCD) including ferroptosis triggered by complex gene-environment …
A novel peptide encoded by N6-methyladenosine modified circMAP3K4 prevents apoptosis in hepatocellular carcinoma
JL Duan, W Chen, JJ Xie, ML Zhang, RC Nie, H Liang… - Molecular cancer, 2022 - Springer
Abstract Background Circular RNAs (circRNAs) regulate various biological activities and
have been shown to play crucial roles in hepatocellular carcinoma (HCC) progression …
have been shown to play crucial roles in hepatocellular carcinoma (HCC) progression …
WTAP-mediated m6A modification of lncRNA DIAPH1-AS1 enhances its stability to facilitate nasopharyngeal carcinoma growth and metastasis
ZX Li, ZQ Zheng, PY Yang, L Lin, GQ Zhou… - Cell Death & …, 2022 - nature.com
As the most predominant RNA epigenetic regulation in eukaryotic cells, N6-
methyladenosine (m6A) plays a critical role in human tumorigenesis and cancer …
methyladenosine (m6A) plays a critical role in human tumorigenesis and cancer …