Cancer metastasis is a malignant process by which tumor cells migrate from their primary
site of origin to other organs. It is the main cause of poor prognosis in cancer patients …

Remodeling of extracellular matrix in the womb facilitates the dramatic morphogenesis of
maternal and placental tissues necessary to support fetal development. In addition to …

Endometrial cancer (EC) is one of the most frequently diagnosed cancers in women, and
despite recent therapeutic advances, in many cases, treatment failure results in cancer …

Endometrial and cervical cancers are the two most common gynaecological malignancies
and among the leading causes of death worldwide. The extracellular matrix (ECM) is an …

Immune evasion—a well-established cancer hallmark—is a major barrier to immunotherapy
efficacy. While the molecular mechanisms and biological consequences underpinning …

The tumor microenvironment is surrounded by blood vessels and consists of malignant,
nonmalignant, and immune cells, as well as signalling molecules, which primarily affect the …

Obesity is responsible for increased morbidity and mortality in endometrial cancer. Despite
the positive correlation of body mass index (BMI) or obesity in endometrial carcinogenesis …

Objective This paper reviews the association between transforming growth factor-β (TGF-β)
and its receptor and tumor, focusing on gynecological malignant tumors. we hope to provide …

The human CST complex composed of CTC1, STN1, and TEN1 is critically involved in
telomere maintenance and homeostasis. Specifically, CST terminates telomere extension by …

Endometrial cancer (EC) is a common female reproductive tumor worldwide. Nonetheless,
the pathogenesis of EC still remains ambiguous and associated epigenetic mechanism still …