Glucuronidation is a listed clearance mechanism for 1 in 10 of the top 200 prescribed drugs.
The objective of this article is to encourage those studying ligand interactions with UDP …

The characterisation of a novel amphiphilic material, Alg-C4, produced from butanol linked
by esterification to alginate is presented. The novel derivative retains the gelling and non …

Metoclopramide hydrochloride (MCP) is commonly used for the management of
gastrointestinal disorders. Frequent administration and the undesired side effects (extra …

An oral sustained release dosage form of cinnarizine HCl (CNZ) based on gastric floating
matrix tablets was studied. The release of CNZ from different floating matrix formulations …

OBJECTIVE: The pattern of dopamine antagonism by metoclopramide suggests benefits in
the treatment of tic disorders. The purpose of this study was to examine the efficacy and …

The new trends in pharmaceutical studies focus on targeting drug delivery and computer
software that help in the body environment simulation, such as Gastroplus® software. The …

In the present work, to maintain a suitable blood level of vinpocetine (VP) for a long period of
time, VP‐cyclodextrin‐tartaric acid multicomponent complexes were prepared and …

Membrane permeability and P-glycoprotein (P-gp) efflux system are regulating factors in the
drug brain penetration. Recently, some drug delivery systems have been developed to …

The present work investigated the utilization of degree of substitution in preparing N-hexoyl
chitosan matrices with superdisintegration power. Different degrees of substitution of N …

In the present work, an attempt has been made to screen Prosopis africana seed gum (PG),
anionic polymer for extended release tablet formulation. Different categories of drugs …