Fluorine-containing indoles: Synthesis and biological activity
EV Nosova, GN Lipunova, VN Charushin… - Journal of Fluorine …, 2018 - Elsevier
Fluorine-containing indoles: Synthesis and biological activity - ScienceDirect Skip to main
contentSkip to article Elsevier logo Journals & Books Search RegisterSign in View PDF …
contentSkip to article Elsevier logo Journals & Books Search RegisterSign in View PDF …
Indol-3-ylglyoxylamide as Privileged Scaffold in Medicinal Chemistry
E Barresi, M Robello, E Baglini, V Poggetti, M Viviano… - Pharmaceuticals, 2023 - mdpi.com
In recent years, indolylglyoxylamide-based derivatives have received much attention due to
their application in drug design and discovery, leading to the development of a wide array of …
their application in drug design and discovery, leading to the development of a wide array of …
Computer-aided discovery of bis-indole derivatives as multi-target drugs against cancer and bacterial infections: DFT, docking, virtual screening, and molecular …
Recently, more complex diseases of seemingly incurable pathology have demonstrated the
need for potent and multi-target drugs. Specific to many cancers and bacterial diseases …
need for potent and multi-target drugs. Specific to many cancers and bacterial diseases …
[HTML][HTML] Oxidative tryptamine dimers from corynebacterium durum directly target survivin to induce AIF-mediated apoptosis in cancer cells
S Kim, M Lee, NY Kim, YS Kwon, GS Nam… - Biomedicine & …, 2024 - Elsevier
Accumulating evidence indicates that microbial communities in the human body crucially
affect health through the production of chemical messengers. However, the relationship …
affect health through the production of chemical messengers. However, the relationship …
Design, synthesis, biological evaluation and molecular modelling studies of indole glyoxylamides as a new class of potential pancreatic lipase inhibitors
SNC Sridhar, S Palawat, AT Paul - Bioorganic Chemistry, 2019 - Elsevier
A series of eighteen indole glyoxylamide analogues were synthesized, characterized and
evaluated for their pancreatic lipase inhibitory activity. Porcine pancreatic lipase (Type II) …
evaluated for their pancreatic lipase inhibitory activity. Porcine pancreatic lipase (Type II) …
Decarboxylative acylation of N-free indoles enabled by a catalytic amount of copper catalyst and liquid-assisted grinding
J Yu, C Zhang, X Yang, W Su - Organic & biomolecular chemistry, 2019 - pubs.rsc.org
A facile decarboxylative acylation of N-free indoles with α-ketonates via liquid-assisted
grinding was reported. The reaction requires only a catalytic amount of Cu (OAc) 2· H2O in …
grinding was reported. The reaction requires only a catalytic amount of Cu (OAc) 2· H2O in …
Recent advances on anticancer and antimicrobial activities of directly-fluorinated five-membered heterocycles and their benzo-fused systems
Due to the importance of the fluorinated heterocycles as main components of marketed
drugs where 20% of the anticancer and antibiotic drugs contain fluorine atoms, this review …
drugs where 20% of the anticancer and antibiotic drugs contain fluorine atoms, this review …
Efficient One-Pot Synthesis of Indolhydroxy Derivatives Catalyzed by SnCl2, DFT Calculations and Docking Study
Y Hakmaoui, A Eşme, RE Ajlaoui, ME Belghiti… - Chemistry Africa, 2022 - Springer
In this work we used an efficient and simple synthesis for the preparation of new
indolhydroxy derivatives that has been performed by the reduction reaction of 2 …
indolhydroxy derivatives that has been performed by the reduction reaction of 2 …
Design, synthesis, evaluation, and molecular modeling studies of indolyl oxoacetamides as potential pancreatic lipase inhibitors
SNC Sridhar, S Palawat, AT Paul - Archiv der Pharmazie, 2020 - Wiley Online Library
A series of indolyl oxoacetamide analogs was synthesized, characterized, and evaluated for
their pancreatic lipase inhibitory activity using porcine pancreatic lipase (type II) and 4 …
their pancreatic lipase inhibitory activity using porcine pancreatic lipase (type II) and 4 …