Nano-drug delivery system targeting tumor microenvironment: a prospective strategy for melanoma treatment

M Xu, S Li - Cancer Letters, 2023 - Elsevier
Melanoma, the most aggressive form of cutaneous malignancy arising from melanocytes, is
frequently characterized by metastasis. Despite considerable progress in melanoma …

Ultrasound‐Sensitive Intelligent Nanosystems: A Promising Strategy for the Treatment of Neurological Diseases

X Pan, W Huang, G Nie, C Wang… - Advanced Materials, 2024 - Wiley Online Library
Neurological diseases are a major global health challenge, affecting hundreds of millions of
people worldwide. Ultrasound therapy plays an irreplaceable role in the treatment of …

[HTML][HTML] Biomimetic nanovaccine-mediated multivalent IL-15 self-transpresentation (MIST) for potent and safe cancer immunotherapy

K Wang, X Zhang, H Ye, X Wang, Z Fan, Q Lu… - Nature …, 2023 - nature.com
Abstract Cytokine therapy, involving interleukin-15 (IL-15), is a promising strategy for cancer
immunotherapy. However, clinical application has been limited due to severe toxicity and …

Tumor-homing and immune-reprogramming cellular nanovesicles for photoacoustic imaging-guided phototriggered precise chemoimmunotherapy

Z Fan, Y Wang, L Li, F Zeng, Q Shang, Y Liao… - ACS …, 2022 - ACS Publications
Many studies have focused on developing effective therapeutic strategies to selectively
destroy primary tumors, eliminate metastatic lesions, and prevent tumor recurrence with …

In Situ Attached Photothermal Immunomodulation-Enhanced Nanozyme for the Inhibition of Postoperative Malignant Glioma Recurrence

D Nie, Y Ling, W Lv, Q Liu, S Deng, J Shi, J Yang… - ACS …, 2023 - ACS Publications
Glioblastoma (GBM) is one of the most challenging malignant brain tumors to treat. Herein,
we describe a nanoenzyme hemostatic matrix strategy with the tumor cavity in situ …

Tumor microenvironment activated photoacoustic-fluorescence bimodal nanoprobe for precise chemo-immunotherapy and immune response tracing of glioblastoma

F Zeng, Z Fan, S Li, L Li, T Sun, Y Qiu, L Nie… - ACS nano, 2023 - ACS Publications
Synergistic therapy strategy and prognostic monitoring of glioblastoma's immune response
to treatment are crucial to optimize patient care and advance clinical outcomes. However …

Genetically engineered cellular nanoparticles for biomedical applications

N Krishnan, FX Peng, A Mohapatra, RH Fang, L Zhang - Biomaterials, 2023 - Elsevier
In recent years, nanoparticles derived from cellular membranes have been increasingly
explored for the prevention and treatment of human disease. With their flexible design and …

Extracellular vesicles in pancreatic cancer immune escape: emerging roles and mechanisms

C Liu, D He, L Li, S Zhang, L Wang, Z Fan… - Pharmacological …, 2022 - Elsevier
Pancreatic cancer (PC) is the most lethal malignancy worldwide due to its delayed diagnosis
and limited treatment options. Despite great progress in clinical trials of immunotherapies for …

[HTML][HTML] Promotion of wound healing by a thermosensitive and sprayable hydrogel with nanozyme activity and anti-inflammatory properties

W Zhang, X Dai, X Jin, M Huang, J Shan… - Smart Materials in …, 2023 - Elsevier
The rapid healing of wounds requires strategies that relieve oxidative stress resulting from
overloaded free radicals and which promote angiogenesis, collagen deposition, and re …

Ultrasmall zirconium carbide nanodots for synergistic photothermal-radiotherapy of glioma

M Yin, X Chen, Q Guo, L Xiao, P Gao, D Zang, J Dong… - Nanoscale, 2022 - pubs.rsc.org
Glioma is characterized by highly invasive, progressive, and lethal features. In addition,
conventional treatments have been poorly effective in treating glioma. To overcome this …