Non-coding RNAs in human health and disease: potential function as biomarkers and therapeutic targets
T Loganathan, GP Doss C - Functional & integrative genomics, 2023 - Springer
Human diseases have been a critical threat from the beginning of human history. Knowing
the origin, course of action and treatment of any disease state is essential. A microscopic …
the origin, course of action and treatment of any disease state is essential. A microscopic …
Candida parapsilosis: from genes to the bedside
R Tóth, J Nosek, HM Mora-Montes… - Clinical microbiology …, 2019 - Am Soc Microbiol
Patients with suppressed immunity are at the highest risk for hospital-acquired infections.
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …
Among these, invasive candidiasis is the most prevalent systemic fungal nosocomial …
Non-coding RNAs in cancer: Platforms and strategies for investigating the genomic “dark matter”
The discovery of the role of non-coding RNAs (ncRNAs) in the onset and progression of
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
malignancies is a promising frontier of cancer genetics. It is clear that ncRNAs are …
Long non-coding RNAs: mechanisms, experimental, and computational approaches in identification, characterization, and their biomarker potential in cancer
A Chowdhary, V Satagopam, R Schneider - Frontiers in Genetics, 2021 - frontiersin.org
Long non-coding RNAs are diverse class of non-coding RNA molecules> 200 base pairs of
length having various functions like gene regulation, dosage compensation, epigenetic …
length having various functions like gene regulation, dosage compensation, epigenetic …
Secondary structure prediction of long noncoding RNA: review and experimental comparison of existing approaches
Motivation In contrast to messenger RNAs, the function of the wide range of existing long
noncoding RNAs (lncRNAs) largely depends on their structure, which determines …
noncoding RNAs (lncRNAs) largely depends on their structure, which determines …
A hybrid approach to assess the structural impact of long noncoding RNA mutations uncovers key NEAT1 interactions in colorectal cancer
E Aydın, E Saus, U Chorostecki, T Gabaldón - IUBMB life, 2023 - Wiley Online Library
Long noncoding RNAs (lncRNAs) are emerging players in cancer and they entail potential
as prognostic biomarkers or therapeutic targets. Earlier studies have identified somatic …
as prognostic biomarkers or therapeutic targets. Earlier studies have identified somatic …
Probing RNA structural landscapes across Candida yeast genomes
U Chorostecki, E Saus, T Gabaldón - Frontiers in Microbiology, 2024 - frontiersin.org
Understanding the intricate roles of RNA molecules in virulence and host-pathogen
interactions can provide valuable insights into combatting infections and improving human …
interactions can provide valuable insights into combatting infections and improving human …
Chemical and enzymatic probing of viral RNAs: From infancy to maturity and beyond
O Gilmer, E Quignon, AC Jousset, JC Paillart… - Viruses, 2021 - mdpi.com
RNA molecules are key players in a variety of biological events, and this is particularly true
for viral RNAs. To better understand the replication of those pathogens and try to block them …
for viral RNAs. To better understand the replication of those pathogens and try to block them …
RNA structure elements conserved between mouse and 59 other vertebrates
In this work, we present a computational screen conducted for functional RNA structures,
resulting in over 100,000 conserved RNA structure elements found in alignments of mouse …
resulting in over 100,000 conserved RNA structure elements found in alignments of mouse …
Transcriptome sequencing approaches to elucidate host–microbe interactions in opportunistic human fungal pathogens
H Hovhannisyan, T Gabaldón - Fungal Physiology and …, 2019 - Springer
Infections caused by opportunistic human fungal pathogens are a source of increasing
medical concern, due to their growing incidence, the emergence of novel pathogenic …
medical concern, due to their growing incidence, the emergence of novel pathogenic …