Phase-Separating Peptides Recruiting Aggregation-Induced Emission Fluorogen for Rapid E. coli Detection

S Maricar, S Gudlur, A Miserez - Analytical Chemistry, 2023 - ACS Publications
Rationally designed biomolecular condensates have found applications primarily as drug-
delivery systems, thanks to their ability to self-assemble under physico-chemical triggers …

Wash-Free Amperometric Escherichia coli Detection via Rapid and Specific Proteolytic Cleavage by Its Outer Membrane OmpT

S Park, K Park, H Cho, J Kwon, K Kim… - Analytical …, 2022 - ACS Publications
Various methods have been developed for the detection of Escherichia coli (E. coli);
however, they are complex and time-consuming. OmpT─ a cell membrane endopeptidase …

Molecular insights into substrate binding of the outer membrane enzyme OmpT

Y Zhang, M Baaden - Catalysts, 2023 - mdpi.com
The enzyme OmpT of the outer membrane of Escherichia coli shows proteolytic activity and
cleaves peptides and proteins. Using molecular dynamics simulations in a fully hydrated …

Free-standing Three‐dimensional Graphene Scaffolds for Protease Functional Assay

ZK Ng, E Yan, G Goyal, S Gudlur, D Kanagavel… - Sensors and Actuators B …, 2024 - Elsevier
Three-dimensional graphene scaffolds (3d-GS) of high porosity possessing good
fluorescence quenching properties are potential candidates for the development of optical …

Rapid Detection of Escherichia coli: Optimized Peptide-Polythiophene Interactions Help Reduce Assay Time and Improve Naked-Eye Detection

G Sinsinbar, S Gudlur, B Liedberg - ACS Applied Materials & …, 2022 - ACS Publications
Recent improvements in methods for rapid detection of microbial contamination in food and
water samples have aided in the development of on-site and point-of-care testing. Early …

Amphiphilic Membrane Environments Regulate Enzymatic Behaviors of Salmonella Outer Membrane Protease

SL Kum, JCS Ho, AN Parikh… - ACS bio & med Chem …, 2021 - ACS Publications
The role of an amphiphilic environment in the functional regulation of integral membrane
proteins is well appreciated but how specific amphiphilic surrounding influences the …

Outer Membrane Protease Regulation and Function in Enterobacterales

YH Cho - rshare.library.torontomu.ca
Bacteria that make their living inside a host face the constant threat of clearance by host
defenses. Such is the case for Escherichia coli, which often harmlessly colonize humans but …