Goods and bads of the endocannabinoid system as a therapeutic target: Lessons learned after 30 years
The cannabis derivative marijuana is the most widely used recreational drug in the Western
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
world and is consumed by an estimated 83 million individuals (∼ 3% of the world …
Enantioselective dicarbofunctionalization of unactivated alkenes by palladium‐catalyzed tandem heck/suzuki coupling reaction
ZM Zhang, B Xu, L Wu, Y Wu, Y Qian… - Angewandte Chemie …, 2019 - Wiley Online Library
A highly enantioselective dicarbofunctionalization of unactivated alkenes was implemented
by a Pd‐catalyzed asymmetric tandem Heck/Suzuki coupling reaction. This reaction …
by a Pd‐catalyzed asymmetric tandem Heck/Suzuki coupling reaction. This reaction …
Aroyl fluorides as bifunctional reagents for dearomatizing fluoroaroylation of benzofurans
X Yu, QY Meng, CG Daniliuc… - Journal of the American …, 2022 - ACS Publications
The 2, 3-dihydrobenzofuran scaffold is widely found in natural products and biologically
active compounds. Herein, dearomatizing 2, 3-fluoroaroylation of benzofurans with aroyl …
active compounds. Herein, dearomatizing 2, 3-fluoroaroylation of benzofurans with aroyl …
Highly enantioselective cross-electrophile aryl-alkenylation of unactivated alkenes
ZX Tian, JB Qiao, GL Xu, X Pang, L Qi… - Journal of the …, 2019 - ACS Publications
Enantioselective cross-electrophile reactions remain a challenging subject in metal
catalysis, and with respect to data, studies have mainly focused on stereoconvergent …
catalysis, and with respect to data, studies have mainly focused on stereoconvergent …
An overview of the cannabinoid type 2 receptor system and its therapeutic potential
B Bie, J Wu, JF Foss, M Naguib - Current Opinion in …, 2018 - journals.lww.com
An overview of the cannabinoid type 2 receptor system and it... : Current Opinion in
Anesthesiology An overview of the cannabinoid type 2 receptor system and its therapeutic …
Anesthesiology An overview of the cannabinoid type 2 receptor system and its therapeutic …
[HTML][HTML] Homology modeling a fast tool for drug discovery: current perspectives
VK Vyas, RD Ukawala, M Ghate… - Indian journal of …, 2012 - ncbi.nlm.nih.gov
Major goal of structural biology involve formation of protein-ligand complexes; in which the
protein molecules act energetically in the course of binding. Therefore, perceptive of protein …
protein molecules act energetically in the course of binding. Therefore, perceptive of protein …
Enantioselective difunctionalization of alkenes by a palladium‐catalyzed heck/sonogashira sequence
L Zhou, S Li, B Xu, D Ji, L Wu, Y Liu… - Angewandte Chemie …, 2020 - Wiley Online Library
Sonogashira‐type cross‐couplings are one of the most significant alkynylations in organic
chemistry. One of the first palladium‐catalyzed intramolecular Heck/Sonogashira reactions …
chemistry. One of the first palladium‐catalyzed intramolecular Heck/Sonogashira reactions …
Palladium‐Catalyzed Enantioselective Reductive Heck Reactions: Convenient Access to 3, 3‐Disubstituted 2, 3‐Dihydrobenzofuran
ZM Zhang, B Xu, Y Qian, L Wu, Y Wu… - Angewandte …, 2018 - Wiley Online Library
The first example of highly enantioselective intramolecular hydroarylation of allyl aryl ethers
was realized by palladium‐catalyzed reductive heck reactions utilizing a new chiral …
was realized by palladium‐catalyzed reductive heck reactions utilizing a new chiral …
Multi-target-directed ligands and other therapeutic strategies in the search of a real solution for Alzheimer's disease
A Agis-Torres, M Sollhuber… - Current …, 2014 - ingentaconnect.com
The lack of an adequate therapy for Alzheimer's Disease (AD) contributes greatly to the
continuous growing amount of papers and reviews, reflecting the important efforts made by …
continuous growing amount of papers and reviews, reflecting the important efforts made by …
Ruthenium (II)‐Catalyzed Asymmetric Inert C− H Bond Activation Assisted by a Chiral Transient Directing Group
G Li, Q Liu, L Vasamsetty, W Guo… - Angewandte Chemie …, 2020 - Wiley Online Library
A ruthenium (II)‐catalyzed asymmetric intramolecular hydroarylation assisted by a chiral
transient directing group has been developed. A series of 2, 3‐dihydrobenzofurans bearing …
transient directing group has been developed. A series of 2, 3‐dihydrobenzofurans bearing …