Arthropod nuclear receptors and their role in molting

Y Nakagawa, VC Henrich - The FEBS journal, 2009 - Wiley Online Library
The molting process in arthropods is regulated by steroid hormones acting via nuclear
receptor proteins. The most common molting hormone is the ecdysteroid, 20 …

Ecdysone receptor agonism leading to lethal molting disruption in arthropods: review and adverse outcome pathway development

Y Song, DL Villeneuve, K Toyota, T Iguchi… - … science & technology, 2017 - ACS Publications
Molting is critical for growth, development, reproduction, and survival in arthropods.
Complex neuroendocrine pathways are involved in the regulation of molting and may …

[HTML][HTML] Diversity and evolution of the P450 family in arthropods

W Dermauw, T Van Leeuwen, R Feyereisen - Insect biochemistry and …, 2020 - Elsevier
The P450 family (CYP genes) of arthropods encodes diverse enzymes involved in the
metabolism of foreign compounds and in essential endocrine or ecophysiological functions …

Ecdysone receptors: from the Ashburner model to structural biology

RJ Hill, IML Billas, F Bonneton… - Annual Review of …, 2013 - annualreviews.org
In 1974, Ashburner and colleagues postulated a model to explain the control of the puffing
sequence on Drosophila polytene chromosomes initiated by the molting hormone 20 …

Ecdysteroid hormone action

KD Spindler, C Hönl, C Tremmel, S Braun… - Cellular and molecular …, 2009 - Springer
Several reviews devoted to various aspects of ecdysone research have been published
during the last few years. Therefore, this article concentrates mainly on the considerable …

The ecdysteroid receptor

VC Henrich - Insect endocrinology, 2012 - Elsevier
Publisher Summary This chapter examines the information gathered about the ecdysteroid
receptor at three levels and provides brief descriptions and references for the tools used to …

Scorpion and spider venom peptides: gene cloning and peptide expression

V Quintero-Hernández, E Ortiz, M Rendón-Anaya… - Toxicon, 2011 - Elsevier
This communication reviews most of the important findings related to venom components
isolated from scorpions and spiders, mainly by means of gene cloning and expression …

Ecdysone receptor isoforms play distinct roles in larval–pupal–adult transition in Leptinotarsa decemlineata

QY Xu, P Deng, Q Zhang, A Li, KY Fu, WC Guo… - Insect …, 2020 - Wiley Online Library
A heterodimer of two nuclear receptors, ecdysone receptor (EcR) and ultraspiracle,
mediates 20‐hydroxyecdysone (20E) signaling to modulate many aspects in insect life, such …

Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties

AM Tarrant, L Behrendt, JJ Stegeman… - General and Comparative …, 2011 - Elsevier
In arthropods, ecdysteroids regulate molting by activating a heterodimer formed by the
ecdysone receptor (EcR) and retinoid X receptor (RXR). While this mechanism is similar in …

Functional characterization of ultraspiracle in Leptinotarsa decemlineata using RNA interference assay

QY Xu, P Deng, A Li, Q Zhang, LL Mu… - Insect Molecular …, 2019 - Wiley Online Library
A heterodimer of ultraspiracle (USP) and ecdysone receptor (EcR) mediates 20‐
hydroxyecdysone (20E) signalling cascade to regulate insect moulting and metamorphosis …