Hepatitis B virus (HBV) is a hepatotropic virus and an important human pathogen. There are
an estimated 296 million people in the world that are chronically infected by this virus, and …

▪ Abstract An unconventional mechanism for retaining improperly folded glycoproteins and
facilitating acquisition of their native tertiary and quaternary structures operates in the …

Increased understanding of the role of protein-and lipid-linked carbohydrates in a wide
range of biological processes has led to interest in drugs that target the enzymes involved in …

N-Linked oligosaccharides play many roles in the fate and functions of glycoproteins. One
function is to assist in the folding of proteins by mediating interactions of the lectin-like …

The development of a new fast, portable and reagent-free diagnostic technique for hepatitis
B (HBV) and hepatitis C (HCV) viruses would be an enormous benefit to society. Here, we …

The endoplasmic reticulum (ER) is the subcellular site where proteins following the
secretory pathway acquire their proper tertiary and, in certain cases, quaternary structures …

One function of N-linked glycans is to assist in the folding of glycoproteins by mediating
interactions of the lectin-like chaperone proteins calnexin and calreticulin with nascent …

Glycosphingolipids (GSL's) are ubiquitous components of the cellular membranes of all
eukaryotic cells, and nearly 300 different structures have been identified. 1 They are …

The hepatitis B virus (HBV) mutation that encodes rtA181T is selected in the viral
polymerase during antiviral drug therapy and can also encode a stop codon in the …

Endoplasmic reticulum (ER) α-glucosidase inhibitors, which block the trimming step of N-
linked glycosylation, have been shown to eliminate the production of several ER-budding …