[HTML][HTML] Microbiota in health and diseases
The role of microbiota in health and diseases is being highlighted by numerous studies
since its discovery. Depending on the localized regions, microbiota can be classified into …
since its discovery. Depending on the localized regions, microbiota can be classified into …
Monounsaturated fatty acids in obesity-related inflammation
G Ravaut, A Légiot, KF Bergeron… - International journal of …, 2020 - mdpi.com
Obesity is an important aspect of the metabolic syndrome and is often associated with
chronic inflammation. In this context, inflammation of organs participating in energy …
chronic inflammation. In this context, inflammation of organs participating in energy …
Metabolomics signatures in type 2 diabetes: a systematic review and integrative analysis
Y Sun, HY Gao, ZY Fan, Y He… - The Journal of Clinical …, 2020 - academic.oup.com
Objective Metabolic signatures have emerged as valuable signaling molecules in the
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …
biochemical process of type 2 diabetes (T2D). To summarize and identify metabolic …
The biological functions and regulatory mechanisms of fatty acid binding protein 5 in various diseases
B Xu, L Chen, Y Zhan, KNS Marquez, L Zhuo… - Frontiers in cell and …, 2022 - frontiersin.org
In recent years, fatty acid binding protein 5 (FABP5), also known as fatty acid transporter,
has been widely researched with the help of modern genetic technology. Emerging …
has been widely researched with the help of modern genetic technology. Emerging …
Lipotoxicity and β-cell failure in type 2 diabetes: Oxidative stress linked to NADPH oxidase and ER stress
A high caloric intake, rich in saturated fats, greatly contributes to the development of obesity,
which is the leading risk factor for type 2 diabetes (T2D). A persistent caloric surplus …
which is the leading risk factor for type 2 diabetes (T2D). A persistent caloric surplus …
Adipose tissue secretion pattern influences β-cell wellness in the transition from obesity to type 2 diabetes
The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …
Selenium Nanodots (SENDs) as Antioxidants and Antioxidant‐Prodrugs to Rescue Islet β Cells in Type 2 Diabetes Mellitus by Restoring Mitophagy and Alleviating …
Q Huang, Z Liu, Y Yang, Y Yang, T Huang… - Advanced …, 2023 - Wiley Online Library
Preventing islet β‐cells death is crucial for treating type 2 diabetes mellitus (T2DM).
Currently, clinical drugs are being developed to improve the quality of T2DM care and self …
Currently, clinical drugs are being developed to improve the quality of T2DM care and self …
Molecular mechanism of palmitic acid and its derivatives in tumor progression
X Wang, C Zhang, N Bao - Frontiers in oncology, 2023 - frontiersin.org
Palmitic acid (PA) is a saturated fatty acid commonly found in coconut oil and palm oil. It
serves as an energy source for the body and plays a role in the structure and function of cell …
serves as an energy source for the body and plays a role in the structure and function of cell …
METTL3 mediates osteoblast apoptosis by regulating endoplasmic reticulum stress during LPS-induced inflammation
Y Kong, Y Zhang, Y Cai, D Li, B Yi, Q Xu - Cellular Signalling, 2022 - Elsevier
Osteoblast apoptosis is a prominent factor for disrupting skeletal homeostasis in multiple
inflammatory bone diseases. METTL3, a key methyltransferase that catalyzes the N6 …
inflammatory bone diseases. METTL3, a key methyltransferase that catalyzes the N6 …
Molecular mechanisms of apoptosis induction and its regulation by fatty acids in pancreatic β-cells
J Šrámek, V Němcová-Fürstová, J Kovář - International Journal of …, 2021 - mdpi.com
Pancreatic β-cell failure and death contribute significantly to the pathogenesis of type 2
diabetes. One of the main factors responsible for β-cell dysfunction and subsequent cell …
diabetes. One of the main factors responsible for β-cell dysfunction and subsequent cell …