Mycoplasma hyopneumoniae: from disease to vaccine development

S Simionatto, SB Marchioro, D Maes… - Veterinary …, 2013 - Elsevier
Mycoplasma hyopneumoniae is the etiological agent of swine enzootic pneumonia (EP), a
disease that affects swine production worldwide. Vaccination is the most cost-effective …

Horizontal gene transfers in mycoplasmas (Mollicutes)

C Citti, E Dordet-Frisoni, LX Nouvel, CH Kuo… - Current issues in …, 2018 - mdpi.com
The class Mollicutes (trivial name" mycoplasma") is composed of wall-less bacteria with
reduced genomes whose evolution was long thought to be only driven by gene losses …

New insights on the biology of swine respiratory tract mycoplasmas from a comparative genome analysis

FM Siqueira, CE Thompson, VG Virginio… - BMC genomics, 2013 - Springer
Abstract Background Mycoplasma hyopneumoniae, Mycoplasma flocculare and
Mycoplasma hyorhinis live in swine respiratory tracts. M. flocculare, a commensal bacterium …

Post-translational processing targets functionally diverse proteins in Mycoplasma hyopneumoniae

JL Tacchi, BBA Raymond, PA Haynes… - Open …, 2016 - royalsocietypublishing.org
Mycoplasma hyopneumoniae is a genome-reduced, cell wall-less, bacterial pathogen with a
predicted coding capacity of less than 700 proteins and is one of the smallest self-replicating …

Characterization of cleavage events in the multifunctional cilium adhesin Mhp684 (P146) reveals a mechanism by which Mycoplasma hyopneumoniae regulates …

DR Bogema, AT Deutscher, LK Woolley, LM Seymour… - MBio, 2012 - Am Soc Microbiol
Mycoplasma hyopneumoniae causes enormous economic losses to swine production
worldwide by colonizing the ciliated epithelium in the porcine respiratory tract, resulting in …

Genomic islands in mycoplasmas

C Citti, E Baranowski, E Dordet-Frisoni, M Faucher… - Genes, 2020 - mdpi.com
Bacteria of the Mycoplasma genus are characterized by the lack of a cell-wall, the use of
UGA as tryptophan codon instead of a universal stop, and their simplified metabolic …

Comparative genomic analyses of Mycoplasma hyopneumoniae pathogenic 168 strain and its high-passaged attenuated strain

W Liu, S Xiao, M Li, S Guo, S Li, R Luo, Z Feng, B Li… - BMC genomics, 2013 - Springer
Background Mycoplasma hyopneumoniae is the causative agent of porcine enzootic
pneumonia (EP), a mild, chronic pneumonia of swine. Despite presenting with low direct …

Mycoplasma hyopneumoniae Infection Activates the NOD1 Signaling Pathway to Modulate Inflammation

W Liu, P Jiang, K Yang, Q Song, F Yuan… - Frontiers in Cellular …, 2022 - frontiersin.org
Mycoplasma hyopneumoniae is a highly contagious pathogen causing porcine enzootic
pneumonia, which elicits prolonged inflammatory response modulated by pattern …

Insights on the virulence of swine respiratory tract mycoplasmas through genome-scale metabolic modeling

MG Ferrarini, FM Siqueira, SG Mucha, TL Palama… - BMC genomics, 2016 - Springer
Background The respiratory tract of swine is colonized by several bacteria among which are
three Mycoplasma species: Mycoplasma flocculare, Mycoplasma hyopneumoniae and …

Microbial communities in swine lungs and their association with lung lesions

T Huang, M Zhang, X Tong, J Chen, G Yan… - Microbial …, 2019 - Wiley Online Library
Under natural farming, environmental pathogenic microorganisms may invade and affect
swine lungs, further resulting in lung lesions. However, few studies on swine lung microbiota …