Muscle‐specific, liver‐detargeted adeno‐associated virus gene therapy rescues Pompe phenotype in adult and neonate Gaa−/− mice

P Sellier, P Vidal, B Bertin, E Gicquel… - Journal of Inherited …, 2024 - Wiley Online Library
Pompe disease (PD) is a neuromuscular disorder caused by acid α‐glucosidase (GAA)
deficiency. Reduced GAA activity leads to pathological glycogen accumulation in cardiac …