Self-healing injectable hydrogels for tissue regeneration

P Bertsch, M Diba, DJ Mooney… - Chemical …, 2022 - ACS Publications
Biomaterials with the ability to self-heal and recover their structural integrity offer many
advantages for applications in biomedicine. The past decade has witnessed the rapid …

[HTML][HTML] Smart/stimuli-responsive hydrogels: Cutting-edge platforms for tissue engineering and other biomedical applications

HM El-Husseiny, EA Mady, L Hamabe, A Abugomaa… - Materials Today Bio, 2022 - Elsevier
Recently, biomedicine and tissue regeneration have emerged as great advances that
impacted the spectrum of healthcare. This left the door open for further improvement of their …

Hydrogel‐based growth factor delivery platforms: strategies and recent advances

BH Shan, FG Wu - Advanced Materials, 2024 - Wiley Online Library
Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

[HTML][HTML] Reactive oxygen species-based nanomaterials for the treatment of myocardial ischemia reperfusion injuries

T Zhao, W Wu, L Sui, Q Huang, Y Nan, J Liu, K Ai - Bioactive Materials, 2022 - Elsevier
Interventional coronary reperfusion strategies are widely adopted to treat acute myocardial
infarction, but morbidity and mortality of acute myocardial infarction are still high …

Development of innovative biomaterials and devices for the treatment of cardiovascular diseases

Y Wang, G Li, L Yang, R Luo, G Guo - Advanced Materials, 2022 - Wiley Online Library
Cardiovascular diseases have become the leading cause of death worldwide. The
increasing burden of cardiovascular diseases has become a major public health problem …

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

D Zhu, Z Li, K Huang, TG Caranasos, JS Rossi… - Nature …, 2021 - nature.com
Cardiac patches are an effective way to deliver therapeutics to the heart. However, such
procedures are normally invasive and difficult to perform. Here, we develop and test a …

Injectable hydrogels with high drug loading through B–N coordination and ROS-triggered drug release for efficient treatment of chronic periodontitis in diabetic rats

X Zhao, Y Yang, J Yu, R Ding, D Pei, Y Zhang, G He… - Biomaterials, 2022 - Elsevier
The clinical management of chronic periodontitis with diabetes mellitus (CPDM) is a long-
standing thorny issue. The excessive production of reactive oxygen species (ROS) is one of …

Cardiac fibrosis: Myofibroblast-mediated pathological regulation and drug delivery strategies

M Liu, BL de Juan Abad, K Cheng - Advanced drug delivery reviews, 2021 - Elsevier
Cardiac fibrosis remains an unresolved problem in heart diseases. After initial injury, cardiac
fibroblasts (CFs) are activated and subsequently differentiate into myofibroblasts (myoFbs) …

Regeneration of infarcted hearts by myocardial infarction-responsive injectable hydrogels with combined anti-apoptosis, anti-inflammatory and pro-angiogenesis …

C Hu, W Liu, L Long, Z Wang, W Zhang, S He, L Lu… - Biomaterials, 2022 - Elsevier
Current treatments including drug therapy, medical device implantation, and organ
transplantation have considerable shortcomings for myocardial infarction (MI), such as high …

A minimally invasive exosome spray repairs heart after myocardial infarction

J Yao, K Huang, D Zhu, T Chen, Y Jiang, J Zhang… - ACS …, 2021 - ACS Publications
Myocardial infarction (MI) remains the most common cause of death worldwide. Many MI
survivors will suffer from recurrent heart failure (HF), which has been recognized as a …