Medicinal plants of the family Lamiaceae in pain therapy: A review

CM Uritu, CT Mihai, GD Stanciu, G Dodi… - Pain Research and …, 2018 - Wiley Online Library
Recently, numerous side effects of synthetic drugs have lead to using medicinal plants as a
reliable source of new therapy. Pain is a global public health problem with a high impact on …

Epigenetic mechanisms of chronic pain

G Descalzi, D Ikegami, T Ushijima, EJ Nestler… - Trends in …, 2015 - cell.com
Neuropathic and inflammatory pain promote a large number of persisting adaptations at the
cellular and molecular level, allowing even transient tissue or nerve damage to elicit …

[HTML][HTML] Epigenetic modifications associated to neuroinflammation and neuropathic pain after neural trauma

C Penas, X Navarro - Frontiers in cellular neuroscience, 2018 - frontiersin.org
Accumulating evidence suggests that epigenetic alterations lie behind the induction and
maintenance of neuropathic pain. Neuropathic pain is usually a chronic condition caused by …

[HTML][HTML] The interplay between oxidative stress, exercise, and pain in health and disease: potential role of autonomic regulation and epigenetic mechanisms

J Hendrix, J Nijs, K Ickmans, L Godderis, M Ghosh… - Antioxidants, 2020 - mdpi.com
Oxidative stress can be induced by various stimuli and altered in certain conditions,
including exercise and pain. Although many studies have investigated oxidative stress in …

Epigenetic regulation of chronic pain

L Liang, BM Lutz, A Bekker, YX Tao - Epigenomics, 2015 - Future Medicine
Chronic pain arising from peripheral inflammation and tissue or nerve injury is a common
clinical symptom. Although intensive research on the neurobiological mechanisms of …

[HTML][HTML] Inflammation and histone modification in chronic pain

W Jiang, LX Zhang, XY Tan, P Yu, M Dong - Frontiers in Immunology, 2023 - frontiersin.org
Increasing evidence suggests that epigenetic mechanisms have great potential in the field of
pain. The changes and roles of epigenetics of the spinal cord and dorsal root ganglia in the …

[HTML][HTML] Histone post-translational modifications as potential therapeutic targets for pain management

JV Torres-Perez, J Irfan, MR Febrianto… - Trends in …, 2021 - cell.com
Effective pharmacological management of pain associated with tissue pathology is an unmet
medical need. Transcriptional modifications in nociceptive pathways are pivotal for the …

[PDF][PDF] 黄芩的化学成分与药理作用研究进展

郑勇凤, 王佳婧, 傅超美, 王建新 - 中成药, 2016 - pmt5b327c-pic7.websiteonline.cn
黄芩为临床常用的清热燥湿药, 主要含有黄酮及其苷类, 萜类化合物及挥发油等成分, 具有解热,
抗炎, 抗微生物, 抗肿瘤, 抗氧化等药理作用, 对消化系统, 心血管系统, 神经系统等疾病具有一定 …

D‐β‐hydroxybutyrate promotes functional recovery and relieves pain hypersensitivity in mice with spinal cord injury

J Qian, W Zhu, M Lu, B Ni, J Yang - British Journal of …, 2017 - Wiley Online Library
Background and Purpose Spinal cord injury (SCI) leads to severe motor and sensory
dysfunction and significantly reduces the quality of life. The aim of the present work was to …

[HTML][HTML] In vitro and in vivo effects of flavonoids on peripheral neuropathic pain

P Basu, A Basu - Molecules, 2020 - mdpi.com
Neuropathic pain is a common symptom and is associated with an impaired quality of life. It
is caused by the lesion or disease of the somatosensory system. Neuropathic pain …