Autophagic pathways cross with lipid homeostasis and thus provide energy and essential
building blocks that are indispensable for liver functions. Energy deficiencies are …

Background Non-alcoholic fatty liver disease (NAFLD) is defined by the abundance of lipid
droplets (LDs) in hepatocytes. While historically considered simply a depot for energy …

Organelle interactions play a significant role in compartmentalizing metabolism and
signaling. Lipid droplets (LDs) interact with numerous organelles, including mitochondria …

Non-alcoholic fatty liver disease (NAFLD) or metabolic (dysfunction) associated liver
disease (MAFLD), is, with a global prevalence of 25%, the most common liver disorder …

Lipid droplets (LDs) are ubiquitous organelles that store and supply lipids for energy
metabolism, membrane synthesis and production of lipid-derived signaling molecules. While …

Aging is associated with many deleterious changes at the cellular level, including the
accumulation of potentially toxic components that can have devastating effects on health. A …

Disturbances in lipid homeostasis can cause mitochondrial dysfunction and lipotoxicity.
Perilipin 5 (PLIN5) decorates intracellular lipid droplets (LDs) in oxidative tissues and …

Abstract Aflatoxin B1 (AFB1) is one of the most toxic mycotoxins widely found in food
contaminants, and its target organ is the liver. It poses a major food security and public …

Studies have found that intermittent fasting (IF) can prevent diabetes, cancer, heart disease,
and neuropathy, while in humans it has helped to alleviate metabolic syndrome, asthma …

Alzheimer's disease (AD) is one of the most common neurodegenerative diseases, and no
effective therapies have been found to prevent or cure AD to date. Berberine and curcumin …