Interactions of the Human Pathogenic Brucella Species with Their Hosts

VL Atluri, MN Xavier, MF de Jong… - Annual review of …, 2011 - annualreviews.org
Brucellosis is a zoonotic infection caused primarily by the bacterial pathogens Brucella
melitensis and B. abortus. It is acquired by consumption of unpasteurized dairy products or …

An evolutionary strategy for a stealthy intracellular Brucella pathogen

A Martirosyan, E Moreno, JP Gorvel - Immunological reviews, 2011 - Wiley Online Library
Brucella is an intracellular bacterial pathogen that causes abortion and infertility in mammals
and leads to a debilitating febrile illness that can progress into a long lasting disease with …

Brucella abortus Uses a Stealthy Strategy to Avoid Activation of the Innate Immune System during the Onset of Infection

E Barquero-Calvo, E Chaves-Olarte, DS Weiss… - PloS one, 2007 - journals.plos.org
Background To unravel the strategy by which Brucella abortus establishes chronic
infections, we explored its early interaction with innate immunity. Methodology/Principal …

Actinobacillosis

M Gottschalk, A Broes - Diseases of swine, 2019 - Wiley Online Library
This chapter provides in‐depth coverage of actinobacillosis including relevance, potential
public health significance, epidemiology, pathogenesis, clinical signs, lesions, diagnosis …

Brucella spp. Virulence Factors and Immunity

MX Byndloss, RM Tsolis - Annual review of animal biosciences, 2016 - annualreviews.org
Brucellosis, caused by bacteria of the genus Brucella, is an important zoonotic infection that
causes reproductive disease in domestic animals and chronic debilitating disease in …

The macrophage paradox

JV Price, RE Vance - Immunity, 2014 - cell.com
Macrophages are a diverse population of phagocytic cells that reside in tissues throughout
the body. At sites of infection, macrophages encounter and engulf invading microbes …

Progress in Brucella vaccine development

X Yang, JA Skyberg, L Cao, B Clapp, T Thornburg… - Frontiers in biology, 2013 - Springer
Brucella spp. are zoonotic, facultative intracellular pathogens, which cause animal and
human disease. Animal disease results in abortion of fetuses; in humans, it manifests flu-like …

Immunity to brucellosis.

P Skendros, P Boura - Revue scientifique et technique …, 2013 - europepmc.org
Resistance to intracellular bacterial pathogens such as Brucella spp. relies on cell-mediated
immunity, which involves activation of the bactericidal mechanisms of antigen-presenting …

PPARγ-mediated increase in glucose availability sustains chronic Brucella abortus infection in alternatively activated macrophages

MN Xavier, MG Winter, AM Spees, AB den Hartigh… - Cell host & …, 2013 - cell.com
Eradication of persistent intracellular bacterial pathogens with antibiotic therapy is often slow
or incomplete. However, strategies to augment antibiotics are hampered by our poor …

[HTML][HTML] Cell-mediated immunity in human brucellosis

P Skendros, G Pappas, P Boura - Microbes and infection, 2011 - Elsevier
Brucella can parasitize within human antigen-presenting cells modifying phagocytosis,
phagolysosome fusion, antigen presentation, cytokine secretion, and apoptosis. Subversion …