Moving towards Personalized Medicine—The Broad Use of Aptamers for Targeted Theranostic

AP Sousa, AC Rocha, C Almeida, MCCG Carneiro… - Applied Sciences, 2023 - mdpi.com
Aptamers are short, single-stranded oligonucleotides synthesized in vitro from a randomized
oligonucleotide library against a specific target. These molecules are capable of binding to a …

Acetic acid alleviates the inflammatory response and liver injury in septic mice by increasing the expression of TRIM40

H Yang, L Meng, D Ai, N Hou, H Li… - Experimental and …, 2019 - spandidos-publications.com
Sepsis remains a significant health care issue in clinical practice due to its high mortality rate
and healthcare cost, despite extensive efforts to better understand the pathophysiology of …

A virtual ELISA to quantitate COVID‐19 antibodies in patient serum

K Simpson, HV Jakubowski - Biochemistry and Molecular …, 2020 - Wiley Online Library
Enzyme‐linked immunosorbent assays (ELISAs) are used widely in biotechnology,
pharmaceutical, and clinical medicine labs. At the same time, they appear to be …

Cytokines are early diagnostic biomarkers of graft-versus-host disease in liver recipients

XQ Meng, XH Chen, Z Sahebally, YN Xu, SY Yin… - … & Pancreatic Diseases …, 2017 - Elsevier
Background Graft-versus-host disease (GVHD) is associated with high mortality. Early
diagnosis is essential to start treatment and to improve outcomes. Because of the …

Integrating bioinformatics tools into inquiry-based molecular biology laboratory education modules

CC Goller, MC Srougi, SH Chen… - Frontiers in …, 2021 - frontiersin.org
The accelerating expansion of online bioinformatics tools has profoundly impacted
molecular biology, with such tools becoming integral to the modern life sciences. As a result …

Assessment of Evidentiary Reasoning in Undergraduate Biology: A Lit Review and Application of the Conceptual Analysis of Disciplinary Evidence (CADE) …

S Liu, C Cai, C Liu, A Samarapungavan… - Trends in Teaching …, 2022 - Springer
Abstract Knowledge of concepts and development of the competence to use that knowledge
are foundational for students learning biology as a disciplinary research practice. One …

Introducing students to protein analysis techniques: Separation and comparative analysis of gluten proteins in various wheat strains

AL Pirinelli, JC Trinidad, NLB Pohl - Journal of Chemical …, 2016 - ACS Publications
Polyacrylamide gel electrophoresis (PAGE) is commonly taught in undergraduate laboratory
classes as a traditional method to analyze proteins. An experiment has been developed to …

Shifting faculty approaches to pedagogy through structured teaching postdoc experiences

SH Chen, CC Goller - Journal of Microbiology & Biology Education, 2019 - Am Soc Microbiol
Many studies confirm the benefit of active learning in STEM teaching. However, many faculty
have been slow to adopt such practices, perhaps due to limited time to learn and implement …

Manipulating leukocyte populations to mimic immune disease states: a novel active approach to teaching flow cytometry to undergraduate immunology students

M Costabile, H Nguyen… - Advances in physiology …, 2020 - journals.physiology.org
Flow cytometry detects and measures the physical and chemical characteristics of cells or
particles. In medical laboratories, flow cytometers are used to quantify changes in cell …

Evaluation of 99mTc‐HYNIC‐VCAM‐1scFv as a Potential Qualitative and Semiquantitative Probe Targeting Various Tumors

X Zhang, F Hu, C Liu, L Yin, Y Zhang… - Contrast Media & …, 2018 - Wiley Online Library
Vascular cell adhesion molecule 1 (VCAM‐1) is overexpressed in varieties of cancers. This
study aimed to evaluate the application of a single chain variable fragment (scFv) of anti …