Broadly neutralizing antibodies target the coronavirus fusion peptide
The potential for future coronavirus outbreaks highlights the need to broadly target this
group of pathogens. We used an epitope-agnostic approach to identify six monoclonal …
group of pathogens. We used an epitope-agnostic approach to identify six monoclonal …
Rare, convergent antibodies targeting the stem helix broadly neutralize diverse betacoronaviruses
Humanity has faced three recent outbreaks of novel betacoronaviruses, emphasizing the
need to develop approaches that broadly target coronaviruses. Here, we identify 55 …
need to develop approaches that broadly target coronaviruses. Here, we identify 55 …
Antibody-mediated immunity to SARS-CoV-2 spike
Despite effective spike-based vaccines and monoclonal antibodies, the SARS-CoV-2
pandemic continues more than two and a half years post-onset. Relentless investigation has …
pandemic continues more than two and a half years post-onset. Relentless investigation has …
A RCT of a third dose CoronaVac or BNT162b2 vaccine in adults with two doses of CoronaVac
CK Pun Mok, SMS Cheng, C Chen, K Yiu, TO Chan… - MedRxiv, 2021 - medrxiv.org
Background Poor immunogenicity and antibody waning were found in vaccinees of
CoronaVac. There is lack of randomized controlled trial (RCT) data to compare the …
CoronaVac. There is lack of randomized controlled trial (RCT) data to compare the …
[HTML][HTML] Age-related seroprevalence trajectories of seasonal coronaviruses in children including neonates in Guangzhou, China
Y Luo, H Lv, S Zhao, Y Sun, C Liu, C Chen… - International Journal of …, 2023 - Elsevier
Objectives Four seasonal coronaviruses, including human coronavirus (HCoV)-229E and
HCoV-OC43, HCoV-NL63, and HCoV-HKU1 cause approximately 15-30% of common colds …
HCoV-OC43, HCoV-NL63, and HCoV-HKU1 cause approximately 15-30% of common colds …
Age-related seroprevalence trajectories of seasonal coronaviruses in children
Y Luo, H Lv, S Zhao, Y Sun, C Liu, C Chen, W Liang… - bioRxiv, 2022 - biorxiv.org
Four seasonal coronaviruses, including HCoV-NL63 and HCoV-229E, HCoV-OC43 and
HCoV-HKU1 cause approximately 15–30% of common colds in adults. However, the …
HCoV-HKU1 cause approximately 15–30% of common colds in adults. However, the …