Advances in neonatal acute kidney injury

MC Starr, JR Charlton, R Guillet, K Reidy… - …, 2021 - publications.aap.org
In this state-of-the-art review, we highlight the major advances over the last 5 years in
neonatal acute kidney injury (AKI). Large multicenter studies reveal that neonatal AKI is …

Physiology and pathophysiology of compensatory adaptations of a solitary functioning kidney

Z McArdle, MF Schreuder, KM Moritz… - Frontiers in …, 2020 - frontiersin.org
Children born with a solitary functioning kidney (SFK) have an increased risk of
hypertension and kidney disease from early in adulthood. In response to a reduction in …

Sensing ultrasound localization microscopy for the visualization of glomeruli in living rats and humans

L Denis, S Bodard, V Hingot, A Chavignon… - …, 2023 - thelancet.com
Background Estimation of glomerular function is necessary to diagnose kidney diseases.
However, the study of glomeruli in the clinic is currently done indirectly through urine and …

A rodent model of human-dose-equivalent 5-fluorouracil: toxicity in the liver, kidneys, and lungs

MC da Silva, LC Fabiano, KC da Costa Salomão… - Antioxidants, 2023 - mdpi.com
5-Fluorouracil (5-FU) is a chemotherapy drug widely used to treat a range of cancer types,
despite the recurrence of adverse reactions. Therefore, information on its side effects when …

Wilms' tumor gene 1: lessons from the interface between kidney development and cancer

E Torban, P Goodyer - American Journal of Physiology …, 2024 - journals.physiology.org
In 1990, mutations of the Wilms' tumor-1 gene (WT1), encoding a transcription factor in the
embryonic kidney, were found in 10–15% of Wilms' tumors; germline WT1 mutations were …

Vertasile ferritin nanocages: applications in detection and bioimaging

Y Chen, C Xu, M Sun, G Zhao, Z Wang, C Lv - Biosensors and …, 2024 - Elsevier
Food safety and human health remain significant concerns in the food industry. Detecting
food contaminants and diagnosing diseases are critical aspects. Ferritin, an iron storage …

Whole organ volumetric sensing Ultrasound Localization Microscopy for characterization of kidney structure

G Chabouh, L Denis, S Bodard, F Lager… - … on Medical Imaging, 2024 - ieeexplore.ieee.org
Glomeruli are the filtration units of the kidney and their function relies heavily on their
microcirculation. Despite its obvious diagnostic importance, an accurate estimation of blood …

Improved small blob detection in 3D images using jointly constrained deep learning and Hessian analysis

Y Xu, T Wu, F Gao, JR Charlton, KM Bennett - Scientific reports, 2020 - nature.com
Imaging biomarkers are being rapidly developed for early diagnosis and staging of disease.
The development of these biomarkers requires advances in both image acquisition and …

Angiotensin II hypertension along the female rat tubule: predicted impact on coupled transport of Na+ and K+

A Edwards, DL Ralph, A Mercado… - American Journal of …, 2023 - journals.physiology.org
Chronic infusion of subpressor level of angiotensin II (ANG II) increases the abundance of
Na+ transporters along the distal nephron, balanced by suppression of Na+ transporters …

Chronic kidney disease in children: an update

L Cirillo, L De Chiara, S Innocenti… - Clinical kidney …, 2023 - academic.oup.com
Chronic kidney disease (CKD) is a major healthcare issue worldwide. However, the
prevalence of pediatric CKD has never been systematically assessed and consistent …