Oxidative stress is characterized by imbalanced reactive oxygen species (ROS) production
and antioxidant defenses. Two main antioxidant systems exist. The nonenzymatic system …

Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …

Reactive oxygen species (ROS) stimulate cell proliferation and induce genetic instability,
and their increase in cancer cells is often viewed as an adverse event. Here, we show that …

Cisplatin-induced nephrotoxicity is associated with gut microbiota disturbance. The present
study aimed to investigate whether supplementation of Lactobacillus reuteri and Clostridium …

Oxidative damage contributes to microbe elimination during macrophage respiratory burst.
Nuclear factor, erythroid-derived 2, like 2 (NRF2) orchestrates antioxidant defenses …

Background: There are close links between chemotherapy-induced intestinal mucositis and
microbiota dysbiosis. Previous studies indicated that D-methionine was an excellent …

Chronic lymphocytic leukemia (CLL) is the most common adult leukemia, and resistance to
fludarabine-based therapies is a major challenge in CLL treatment. Because CLL cells are …

Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of individuals infected with the protozoan parasite Trypanosoma cruzi. Since the …

Trypanosoma cruzi (T. cruzi) is the causative agent for Chagas disease (CD). There is a
critical lack of methods for prevention of infection or treatment of acute infection and chronic …

Chagas disease is caused by the parasite Trypanosoma cruzi. It is a common cause of heart
disease in endemic areas of Latin America. The year 2009 marks the 100th anniversary of …