Lower brain glucose metabolism is present before the onset of clinically measurable
cognitive decline in two groups of people at risk of Alzheimer's disease---carriers of …

Quantitative positron emission tomography (PET) brain studies often require that the input
function be measured, typically via arterial cannulation. Image-derived input function (IDIF) …

Context: Recent studies examining brown adipose tissue (BAT) metabolism in adult humans
have provided convincing evidence of its thermogenic potential and role in clearing …

Indirect evidence from human studies suggests that brown adipose tissue (BAT)
thermogenesis is fueled predominantly by fatty acids hydrolyzed from intracellular …

Key points Both brown adipose tissue (BAT) and skeletal muscle activation contribute to the
metabolic response of acute cold exposure in healthy men even under minimal shivering …

Spontaneous glucose uptake by brown adipose tissue (BAT) is lower in overweight or obese
individuals and in diabetes. However, BAT metabolism has not been previously investigated …

In rodents, brown adipose tissue (BAT) plays an important role in producing heat to defend
against the cold and can metabolize large amounts of dietary fatty acids (DFA). The role of …

Purpose The PET scanners with long axial field of view (AFOV) having~ 20 times higher
sensitivity than conventional scanners provide new opportunities for enhanced parametric …

Pharmacokinetic modelling with arterial sampling is the gold standard for analysing dynamic
PET data of the brain. However, the invasive character of arterial sampling prevents its …

While brown adipose tissue (BAT) is activated by the beta-3-adrenergic receptor (ADRB3) in
rodents, in human brown adipocytes, the ADRB2 is dominantly present and responsible for …