Diabetes and ischemic stroke: an old and new relationship an overview of the close interaction between these diseases

CD Maida, M Daidone, G Pacinella, RL Norrito… - International Journal of …, 2022 - mdpi.com
Diabetes mellitus is a comprehensive expression to identify a condition of chronic
hyperglycemia whose causes derive from different metabolic disorders characterized by …

Endothelial dysfunction and chronic inflammation: the cornerstones of vascular alterations in age-related diseases

G Pacinella, AM Ciaccio, A Tuttolomondo - International Journal of …, 2022 - mdpi.com
Vascular diseases of the elderly are a topic of enormous interest in clinical practice, as they
have great epidemiological significance and lead to ever-increasing healthcare …

[HTML][HTML] Targeting autonomic nervous system as a biomarker of well-ageing in the prevention of stroke

JC Barthelemy, V Pichot, D Hupin, M Berger… - Frontiers in aging …, 2022 - frontiersin.org
Stroke prediction is a key health issue for preventive medicine. Atrial fibrillation (AF)
detection is well established and the importance of obstructive sleep apneas (OSA) has …

Is the TOAST classification suitable for use in personalized medicine in ischemic stroke?

SA Simonsen, AS West, AV Heiberg, F Wolfram… - Journal of personalized …, 2022 - mdpi.com
Pathophysiologic classification of ischemic stroke is essential to a personalized approach to
stroke treatment. The Trial of Org 101072 in Acute Stroke Treatment (TOAST) classification is …

Sleep apnoea and endothelial dysfunction: An individual patient data meta-analysis

V Bironneau, R Tamisier, W Trzepizur… - Sleep Medicine …, 2020 - Elsevier
We performed an individual patient data meta-analysis to investigate the association
between obstructive sleep apnoea (OSA) severity and the reactive hyperaemia index (RHI) …

Endothelial dysfunction and inflammation in ischemic stroke pathogenesis

A Tuttolomondo, M Daidone… - Current Pharmaceutical …, 2020 - ingentaconnect.com
Stroke is a heterogeneous disease, and within the broad category of brain ischemia and its
subtypes vary dramatically in its etiology. The endothelium can regulate the vascular …

Efficacy of dulaglutide on vascular health indexes in subjects with type 2 diabetes: a randomized trial

A Tuttolomondo, A Cirrincione, A Casuccio… - Cardiovascular …, 2021 - Springer
Background Recent cardiovascular outcome trials have shown significant reductions in
major cardiovascular (CV) events with glucagon-like peptide (GLP)-1 receptor agonists …

Role of regular physical activity in neuroprotection against acute ischemia

D Di Raimondo, G Rizzo, G Musiari… - International Journal of …, 2020 - mdpi.com
One of the major obstacles that prevents an effective therapeutic intervention against
ischemic stroke is the lack of neuroprotective agents able to reduce neuronal damage; this …

Separate and combined effects of empagliflozin and semaglutide on vascular function: A 32‐week randomized trial

L Vernstrøm, S Gullaksen, SS Sørensen… - Diabetes, Obesity …, 2024 - Wiley Online Library
Aim Despite the increasing use of combination treatment with sodium‐glucose cotransporter
2 inhibitors and glucagon‐like peptide‐1 receptor agonists, data are limited on the effects of …

Hypertension, arterial stiffness, and clinical outcomes: a cohort study of Chinese community-based population

Z Zhou, AJ Xing, JN Zhang, WH Xia, C Su, SY Xu… - …, 2021 - Am Heart Assoc
Whether the combination of different blood pressure and arterial stiffness (AS) status is
independently associated with clinical outcomes in community dwellers has not been fully …