Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

Estrogen receptors alpha (ERα) and beta (ERβ) are nuclear transcription factors that are
involved in the regulation of many complex physiological processes in humans. Modulation …

By eliciting distinct transcriptional responses, the oestrogen receptors (ERs) ERα and ERβ
exert opposite effects on cellular processes that include proliferation, apoptosis and …

Although most lung cancers are a result of smoking, approximately 25% of lung cancer
cases worldwide are not attributable to tobacco use, accounting for over 300,000 deaths …

Estrogen receptors are broadly expressed in many cell types involved in the innate and
adaptive immune responses, and differentially regulate the production of cytokines. While …

Estrogen has been postulated as a contributor for lung cancer development and
progression. We reviewed the current knowledge about the expression and prognostic …

Accumulating evidence suggests that gender affects the incidence, susceptibility and
severity of several lung diseases. Gender also influences lung development and physiology …

It is estimated that approximately 25% of all lung cancer cases are observed in never-
smokers and its incidence is expected to increase due to smoking prevention programs …

Background Many breast, pancreatic, colonic and non-small-cell lung carcinoma lines
express CEACAM6 (NCA-90) and CEACAM5 (carcinoembryonic antigen, CEA), and …

The involvement of estrogen and its receptors in the development of cancer has been known
for years. However, the exact mechanism responsible is far from clear. The estrogen …