Hepatic macrophages: Key players in the development and progression of liver fibrosis

D Cheng, J Chai, H Wang, L Fu, S Peng… - Liver …, 2021 - Wiley Online Library
Hepatic fibrosis is a common pathological process involving persistent liver injury with
various etiologies and subsequent inflammatory responses that occur in chronic liver …

[HTML][HTML] Novel biomarkers for the management of chronic hepatitis B

T Inoue, Y Tanaka - Clinical and molecular hepatology, 2020 - ncbi.nlm.nih.gov
Hepatitis B virus (HBV) cannot be eliminated completely from infected hepatocytes because
of the presence of intrahepatic covalently closed circular DNA (cccDNA). As chronic hepatitis …

[PDF][PDF] Ipragliflozin improves the hepatic outcomes of patients with diabetes with NAFLD

H Takahashi, T Kessoku, M Kawanaka… - Hepatology …, 2022 - Wiley Online Library
Sodium glucose cotransporter‐2 inhibitors (SGLT2is) are now widely used to treat diabetes,
but their effects on nonalcoholic fatty liver disease (NAFLD) remain to be determined. We …

Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis

K Shirabe, Y Bekki, D Gantumur, K Araki, N Ishii… - Journal of …, 2018 - Springer
Assessing liver fibrosis is important for predicting the efficacy of antiviral therapy and patient
prognosis. Liver biopsy is the gold standard for diagnosing liver fibrosis, despite its …

Association between Wisteria floribunda agglutinin-positive Mac-2 binding protein and the fibrosis stage of non-alcoholic fatty liver disease

M Abe, T Miyake, A Kuno, Y Imai, Y Sawai… - Journal of …, 2015 - Springer
Background Accurately evaluating liver fibrosis in patients with non-alcoholic fatty liver
disease (NAFLD) is important for identifying those who may develop complications. The …

[HTML][HTML] Protein glycosylation as a diagnostic and prognostic marker of chronic inflammatory gastrointestinal and liver diseases

X Verhelst, AM Dias, JF Colombel, S Vermeire… - Gastroenterology, 2020 - Elsevier
Glycans are sequences of carbohydrates that are added to proteins or lipids to modulate
their structure and function. Glycans modify proteins required for regulation of immune cells …

Liver cirrhosis: evaluation, nutritional status, and prognosis

H Nishikawa, Y Osaki - Mediators of inflammation, 2015 - Wiley Online Library
The liver is the major organ for the metabolism of three major nutrients: protein, fat, and
carbohydrate. Chronic hepatitis C virus infection is the major cause of chronic liver disease …

Serum Wisteria floribunda agglutinin-positive Mac-2-binding protein level predicts liver fibrosis and prognosis in primary biliary cirrhosis

T Umemura, S Joshita, T Sekiguchi… - Official journal of the …, 2015 - journals.lww.com
OBJECTIVES: Noninvasive markers of liver fibrosis in patients with primary biliary cirrhosis
(PBC) are needed for predicting disease progression. As theWisteria floribundaagglutinin …

Hepatic stellate cells secreting WFA+‐M2BP: Its role in biological interactions with Kupffer cells

Y Bekki, T Yoshizumi, S Shimoda, S Itoh… - Journal of …, 2017 - Wiley Online Library
Abstract Background and Aim Hepatic stellate cells (HSCs) play a central role in hepatic
fibrosis and are regulated by Kupffer cells (KCs). Wisteria floribunda agglutinin‐positive Mac …

[HTML][HTML] Liver fibrosis markers of nonalcoholic steatohepatitis

H Enomoto, Y Bando, H Nakamura… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is one of the major causes of chronic liver injury.
NAFLD includes a wide range of clinical conditions from simple steatosis to nonalcoholic …