Gut barrier disruption and chronic disease
The intestinal barrier protects the host against gut microbes, food antigens, and toxins
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
present in the gastrointestinal tract. However, gut barrier integrity can be affected by intrinsic …
[HTML][HTML] Short chain fatty acids and its producing organisms: An overlooked therapy for IBD?
The gut microbiome and the intestinal immune system are driving contributors to
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …
inflammatory bowel diseases (IBD). Both have an important signalling factor in common …
Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome
How intestinal microbes regulate metabolic syndrome is incompletely understood. We show
that intestinal microbiota protects against development of obesity, metabolic syndrome, and …
that intestinal microbiota protects against development of obesity, metabolic syndrome, and …
The metabolic nature of inflammatory bowel diseases
TE Adolph, M Meyer, J Schwärzler, L Mayr… - Nature Reviews …, 2022 - nature.com
Crohn's disease and ulcerative colitis, phenotypically comprising a spectrum of inflammatory
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …
bowel diseases (IBDs), spread globally during the westernization of lifestyle and dietary …
[HTML][HTML] Excessive intake of sugar: An accomplice of inflammation
X Ma, F Nan, H Liang, P Shu, X Fan, X Song… - Frontiers in …, 2022 - frontiersin.org
High sugar intake has long been recognized as a potential environmental risk factor for
increased incidence of many non-communicable diseases, including obesity, cardiovascular …
increased incidence of many non-communicable diseases, including obesity, cardiovascular …
Leveraging diet to engineer the gut microbiome
M Wolter, ET Grant, M Boudaud, A Steimle… - Nature reviews …, 2021 - nature.com
Autoimmune diseases, including inflammatory bowel disease, multiple sclerosis and
rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut …
rheumatoid arthritis, have distinct clinical presentations but share underlying patterns of gut …
[HTML][HTML] Microbiome-based interventions to modulate gut ecology and the immune system
The gut microbiome lies at the intersection between the environment and the host, with the
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
ability to modify host responses to disease-relevant exposures and stimuli. This is evident in …
Diet fuelling inflammatory bowel diseases: preclinical and clinical concepts
TE Adolph, J Zhang - Gut, 2022 - gut.bmj.com
The diet and gut microbiota have been extensively interrogated as a fuel for gut
inflammation in inflammatory bowel diseases (IBDs) in the last few years. Here, we review …
inflammation in inflammatory bowel diseases (IBDs) in the last few years. Here, we review …
[HTML][HTML] The role of diet in shaping human gut microbiota
E Rinninella, E Tohumcu, P Raoul, M Fiorani… - Best Practice & …, 2023 - Elsevier
Gut microbiota plays a fundamental role within human health, and exerts key functions
within the human body. Diet is one of the most powerful modulators of gut microbiota …
within the human body. Diet is one of the most powerful modulators of gut microbiota …
[HTML][HTML] Dietary patterns and gut microbiota changes in inflammatory bowel disease: current insights and future challenges
J Yan, L Wang, Y Gu, H Hou, T Liu, Y Ding, H Cao - Nutrients, 2022 - mdpi.com
Inflammatory bowel disease (IBD) is a result of a complex interplay between genes, host
immune response, gut microbiota, and environmental factors. As one of the crucial …
immune response, gut microbiota, and environmental factors. As one of the crucial …