Amino acids are fundamental building blocks supporting life. Their role in protein synthesis
is well defined, but they contribute to a host of other intracellular metabolic pathways …

The increasingly recognized role of different types of B cells and plasma cells in protective
and pathogenic immune responses combined with technological advances have generated …

Antibodies produced by antibody-secreting plasma cells (ASCs) underlie multiple forms of
long-lasting immunity. Here we examined the mechanisms regulating ASC turnover and …

These guidelines are a consensus work of a considerable number of members of the
immunology and flow cytometry community. They provide the theory and key practical …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccines are
effective at protecting from severe disease, but the protective antibodies wane rapidly even …

Germinal centers (GCs) are the site of antibody diversification and affinity maturation and as
such are vitally important for humoral immunity. The study of GC biology has undergone a …

Chronic autoimmune diseases, and in particular Systemic Lupus Erythematosus (SLE), are
endowed with a long‐standing autoreactive B‐cell compartment that is presumed to …

The endoplasmic reticulum (ER) is a critical organelle for protein synthesis, folding and
modification, and lipid synthesis and calcium storage. Dysregulation of ER functions leads to …

The third edition of Flow Cytometry Guidelines provides the key aspects to consider when
performing flow cytometry experiments and includes comprehensive sections describing …

Durable humoral immunity is mediated by long-lived plasma cells (LLPCs) that reside in the
bone marrow. It remains unclear whether severe acute respiratory syndrome coronavirus 2 …