The anesthesiologist's role has expanded beyond the operating room, and anesthesiologist-
led care teams can deliver coordinated care that spans the entire surgical experience, from …

Background Dexmedetomidine is increasingly used for surgical patients requiring general
anaesthesia. However, its effectiveness on patient-centred outcomes remains uncertain. Our …

Clinical practice guidelines are a valuable resource aiding medical decision-making based
on scientific evidence. In anaesthesia, guidelines are increasing in both number and scope …

Patient-oriented research is an emerging approach that engages patients, clinicians, and
researchers to ensure focus on patient-identified priorities. 1 From a clinical perspective …

Background There is controversy regarding optimal use of benzodiazepines during cardiac
surgery, and it is unknown whether and to what extent there is variation in practice. We …

Introduction The Fragility Index (FI) and the FI family are statistical tools that measure the
robustness of randomized controlled trials (RCT) by examining how many patients would …

Background Clinical practice guidelines (CPG) are statements that provide
recommendations regarding the approach to different diseases and aim to increase quality …

Background Postoperative delirium is a serious complication that can occur within the 5th
postoperative day. In 2017, the European Society of Anesthesiologists delivered dedicated …

Evidence in perioperative care is insufficient. There is an urgent need for large perioperative
research programmes, including pragmatic randomised trials, testing daily clinical …

Clinical practice guidelines are increasingly important to guide clinical care. However, they
can vary widely in quality, and many recommendations are based on low-level evidence …