[HTML][HTML] Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers
S Haddadzadegan, F Dorkoosh… - Advanced drug delivery …, 2022 - Elsevier
The oral administration of therapeutic peptides and proteins is favoured from a patient and
commercial point of view. In order to reach the systemic circulation after oral administration …
commercial point of view. In order to reach the systemic circulation after oral administration …
Non-invasive delivery strategies for biologics
AC Anselmo, Y Gokarn, S Mitragotri - Nature Reviews Drug Discovery, 2019 - nature.com
Biologics now constitute a significant element of available medical treatments. Owing to their
clinical and commercial success, biologics are a rapidly growing class and have become a …
clinical and commercial success, biologics are a rapidly growing class and have become a …
Advances in nanoparticulate drug delivery approaches for sublingual and buccal administration
S Hua - Frontiers in pharmacology, 2019 - frontiersin.org
The sublingual and buccal routes of administration have significant advantages for both
local and systemic drug delivery. They have shown to be an effective alternative to the …
local and systemic drug delivery. They have shown to be an effective alternative to the …
Ionic liquid-mediated delivery of insulin to buccal mucosa
A Vaidya, S Mitragotri - Journal of Controlled Release, 2020 - Elsevier
Buccal drug delivery offers a potential non-invasive means of delivering therapeutics to
patients. Despite the promise, the feasibility of transporting proteins and peptides into …
patients. Despite the promise, the feasibility of transporting proteins and peptides into …
An updated overview of the emerging role of patch and film-based buccal delivery systems
Buccal mucosal membrane offers an attractive drug-delivery route to enhance both systemic
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …
and local therapy. This review discusses the benefits and drawbacks of buccal drug delivery …
Novel and revisited approaches in nanoparticle systems for buccal drug delivery
AS Macedo, PM Castro, L Roque, NG Thomé… - Journal of Controlled …, 2020 - Elsevier
The buccal route is considered patient friendly due to its non-invasive nature and ease of
administration. Such delivery route has been used as an alternative for the delivery of drugs …
administration. Such delivery route has been used as an alternative for the delivery of drugs …
Evaluation of photodynamic therapy on nanoparticles and films loaded-nanoparticles based on chitosan/alginate for curcumin delivery in oral biofilms
ALP Silvestre, AM Dos Santos, AB de Oliveira… - International Journal of …, 2023 - Elsevier
Nanoparticles and nanoparticle-loaded films based on chitosan/sodium alginate with
curcumin (CUR) are promising strategies to improve the efficacy of antimicrobial …
curcumin (CUR) are promising strategies to improve the efficacy of antimicrobial …
Methacrylated chitosan as a polymer with enhanced mucoadhesive properties for transmucosal drug delivery
Chitosan is a cationic polysaccharide that exhibits mucoadhesive properties which allow it to
adhere to mucosal tissues. In this work, we explored chemical modification of chitosan …
adhere to mucosal tissues. In this work, we explored chemical modification of chitosan …
Buccal delivery of small molecules and biologics: of mucoadhesive polymers, films, and nanoparticles–an update
VV Nair, P Cabrera, C Ramírez-Lecaros… - International Journal of …, 2023 - Elsevier
Buccal delivery of small and large molecules is an attractive route of administration that has
been studied extensively over the past few decades. This route bypasses first-pass …
been studied extensively over the past few decades. This route bypasses first-pass …
Advances in buccal and oral delivery of insulin
Diabetes mellitus is a metabolic endocrine disease characterized by chronic hyperglycemia
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …
with disturbances in metabolic processes, such as those related to carbohydrates, fat, and …