Managing resistance to immune checkpoint inhibitors in lung cancer: treatment and novel strategies
A Passaro, J Brahmer, S Antonia, T Mok… - Journal of Clinical …, 2022 - ascopubs.org
A proportion of patients with lung cancer experience long-term clinical benefit with immune
checkpoint inhibitors (ICIs). However, most patients develop disease progression during …
checkpoint inhibitors (ICIs). However, most patients develop disease progression during …
TMB or not TMB as a biomarker: That is the question
Immune checkpoint inhibitors (ICIs) have revolutionized the landscape of therapeutic
options for many cancers. These treatments have demonstrated improved efficacy and often …
options for many cancers. These treatments have demonstrated improved efficacy and often …
[HTML][HTML] Differential influence of antibiotic therapy and other medications on oncological outcomes of patients with non-small cell lung cancer treated with first-line …
A Cortellini, M Di Maio, O Nigro, A Leonetti… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Some concomitant medications including antibiotics (ATB) have been
reproducibly associated with worse survival following immune checkpoint inhibitors (ICIs) in …
reproducibly associated with worse survival following immune checkpoint inhibitors (ICIs) in …
Differential prognostic effect of systemic inflammation in patients with non–small cell lung cancer treated with immunotherapy or chemotherapy: A post hoc analysis of …
Background A proinflammatory diathesis, as measured by the neutrophil to lymphocyte ratio
(NLR), heralds an adverse disease course for non–small cell lung cancer (NSCLC) …
(NLR), heralds an adverse disease course for non–small cell lung cancer (NSCLC) …
Prognostic scores including peripheral blood-derived inflammatory indices in patients with advanced non-small-cell lung cancer treated with immune checkpoint …
SE Rebuzzi, A Prelaj, A Friedlaender… - Critical Reviews in …, 2022 - Elsevier
Peripheral blood inflammatory indices, like the neutrophil-to-lymphocyte ratio (NLR), may
reflect the host's pro-inflammatory status and systemic immune response to cancer-related …
reflect the host's pro-inflammatory status and systemic immune response to cancer-related …
[HTML][HTML] Neoadjuvant immunotherapy: a promising new standard of care
E Boydell, JL Sandoval, O Michielin, M Obeid… - International Journal of …, 2023 - mdpi.com
Neoadjuvant immunotherapy has emerged as a promising approach in the treatment of
various malignancies, with preclinical studies showing improved immune responses in the …
various malignancies, with preclinical studies showing improved immune responses in the …
[HTML][HTML] First-line immunotherapy in advanced non-small-cell lung cancer patients with ECOG performance status 2: results of an International Expert Panel Meeting …
Background Immunotherapy represents the standard of care in the first-line treatment of
advanced non-small-cell lung cancer (NSCLC), either as monotherapy in high programmed …
advanced non-small-cell lung cancer (NSCLC), either as monotherapy in high programmed …
[HTML][HTML] Liver metastases and the efficacy of immune checkpoint inhibitors in advanced lung cancer: A systematic review and meta-analysis
H Xia, W Zhang, Y Zhang, X Shang, Y Liu… - Frontiers in …, 2022 - frontiersin.org
Background Liver metastasis is the most common type of lung cancer metastasis, and is a
significant prognostic factor in lung cancer. However, the effect of liver metastases on the …
significant prognostic factor in lung cancer. However, the effect of liver metastases on the …
[HTML][HTML] Efficacy outcomes and prognostic factors from real-world patients with advanced non-small-cell lung cancer treated with first-line chemoimmunotherapy: The …
GL Banna, O Cantale, S Muthuramalingam… - International …, 2022 - Elsevier
Background Efficacy outcomes and prognostic factors of real-world patients with advanced
non-small cell lung cancer (aNSCLC) treated with first-line chemoimmunotherapy are still …
non-small cell lung cancer (aNSCLC) treated with first-line chemoimmunotherapy are still …
Biological Rationale for Peripheral Blood Cell–Derived Inflammatory Indices and Related Prognostic Scores in Patients with Advanced Non-Small-Cell Lung Cancer
Purpose of review To describe the biological rationale of peripheral blood cells (PBC)–
derived inflammatory indexes and assess the related prognostic scores for patients with …
derived inflammatory indexes and assess the related prognostic scores for patients with …