Compare and contrast: pediatric cancer versus adult malignancies
P Kattner, H Strobel, N Khoshnevis, M Grunert… - Cancer and Metastasis …, 2019 - Springer
Cancer is a leading cause of death in both adults and children, but in terms of absolute
numbers, pediatric cancer is a relatively rare disease. The rarity of pediatric cancer is …
numbers, pediatric cancer is a relatively rare disease. The rarity of pediatric cancer is …
Central precocious puberty: recent advances in understanding the aetiology and in the clinical approach
Central precocious puberty (CPP) results from early activation of the hypothalamic‐pituitary‐
gonadal (HPG) axis. The current state of knowledge of the complex neural network acting at …
gonadal (HPG) axis. The current state of knowledge of the complex neural network acting at …
Puberty timing associated with diabetes, cardiovascular disease and also diverse health outcomes in men and women: the UK Biobank study
Early puberty timing is associated with higher risks for type 2 diabetes (T2D) and
cardiovascular disease in women and therefore represents a potential target for early …
cardiovascular disease in women and therefore represents a potential target for early …
Pubertal timing and breast cancer risk in the Sister Study cohort
Background Earlier age at menarche is an established risk factor for breast cancer. While
age at menarche has been fairly stable over the past half-century, age at breast …
age at menarche has been fairly stable over the past half-century, age at breast …
Neither soyfoods nor isoflavones warrant classification as endocrine disruptors: a technical review of the observational and clinical data
M Messina, SB Mejia, A Cassidy… - Critical Reviews in …, 2022 - Taylor & Francis
Soybeans are a rich source of isoflavones, which are classified as phytoestrogens. Despite
numerous proposed benefits, isoflavones are often classified as endocrine disruptors, based …
numerous proposed benefits, isoflavones are often classified as endocrine disruptors, based …
Environmental estrogen-like endocrine disrupting chemicals and breast cancer
Background Estrogen-mimicking endocrine disruptors (EEDs) such as polychlorinated
biphenyls (PCBs), bisphenol A (BPA), and phthalates have been found ubiquitously …
biphenyls (PCBs), bisphenol A (BPA), and phthalates have been found ubiquitously …
Delayed puberty—phenotypic diversity, molecular genetic mechanisms, and recent discoveries
SR Howard, L Dunkel - Endocrine reviews, 2019 - academic.oup.com
This review presents a comprehensive discussion of the clinical condition of delayed
puberty, a common presentation to the pediatric endocrinologist, which may present both …
puberty, a common presentation to the pediatric endocrinologist, which may present both …
Faster ticking rate of the epigenetic clock is associated with faster pubertal development in girls
Epigenetic age is an indicator of biological aging, capturing the impact of environmental and
behavioral influences across time on cellular function. Deviance between epigenetic age …
behavioral influences across time on cellular function. Deviance between epigenetic age …
Adult consequences of self-limited delayed puberty
J Zhu, YM Chan - Pediatrics, 2017 - publications.aap.org
Methods The PubMed database was searched using the following medical subject heading
terms and keywords: delayed puberty, adult height, BMD, fracture, depression, substance …
terms and keywords: delayed puberty, adult height, BMD, fracture, depression, substance …
[HTML][HTML] Understanding the genetic complexity of puberty timing across the allele frequency spectrum
Pubertal timing varies considerably and is associated with later health outcomes. We
performed multi-ancestry genetic analyses on~ 800,000 women, identifying 1,080 signals for …
performed multi-ancestry genetic analyses on~ 800,000 women, identifying 1,080 signals for …