[HTML][HTML] Brain GABA and glutamate levels across pain conditions: a systematic literature review and meta-analysis of 1H-MRS studies using the MRS-Q quality …
Background A proposed mechanism of chronic pain is dysregulation between the main
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …
VeSPA: integrated applications for RF pulse design, spectral simulation and MRS data analysis
Purpose The Vespa package (Versatile Simulation, Pulses, and Analysis) is described and
demonstrated. It provides workflows for developing and optimizing linear combination …
demonstrated. It provides workflows for developing and optimizing linear combination …
[HTML][HTML] In vivo brain GSH: MRS methods and clinical applications
F Bottino, M Lucignani, A Napolitano, F Dellepiane… - Antioxidants, 2021 - mdpi.com
Glutathione (GSH) is an important antioxidant implicated in several physiological functions,
including the oxidation− reduction reaction balance and brain antioxidant defense against …
including the oxidation− reduction reaction balance and brain antioxidant defense against …
The trajectory of cortical GABA across the lifespan, an individual participant data meta-analysis of edited MRS studies
γ-Aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the human brain
and can be measured with magnetic resonance spectroscopy (MRS). Conflicting accounts …
and can be measured with magnetic resonance spectroscopy (MRS). Conflicting accounts …
Osprey: Open-source processing, reconstruction & estimation of magnetic resonance spectroscopy data
Background Processing and quantitative analysis of magnetic resonance spectroscopy
(MRS) data are far from standardized and require interfacing with third-party software. Here …
(MRS) data are far from standardized and require interfacing with third-party software. Here …
Spectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations
Spectral editing in in vivo 1H‐MRS provides an effective means to measure low‐
concentration metabolite signals that cannot be reliably measured by conventional MRS …
concentration metabolite signals that cannot be reliably measured by conventional MRS …
Big GABA II: Water-referenced edited MR spectroscopy at 25 research sites
Accurate and reliable quantification of brain metabolites measured in vivo using 1 H
magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from …
magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from …
MRSCloud: A cloud‐based MRS tool for basis set simulation
Purpose The purpose of this study is to present a cloud‐based spectral simulation tool
“MRSCloud,” which allows MRS users to simulate a vendor‐specific and sequence‐specific …
“MRSCloud,” which allows MRS users to simulate a vendor‐specific and sequence‐specific …
Comparison of seven modelling algorithms for γ‐aminobutyric acid–edited proton magnetic resonance spectroscopy
Edited MRS sequences are widely used for studying γ‐aminobutyric acid (GABA) in the
human brain. Several algorithms are available for modelling these data, deriving metabolite …
human brain. Several algorithms are available for modelling these data, deriving metabolite …
[HTML][HTML] Cortical inhibition in neurofibromatosis type 1 is modulated by lovastatin, as demonstrated by a randomized, triple-blind, placebo-controlled clinical trial
Abstract Neurofibromatosis type 1 (NF1) is associated with GABAergic dysfunction which
has been suggested as the underlying cause of cognitive impairments. Previous intervention …
has been suggested as the underlying cause of cognitive impairments. Previous intervention …