Background A proposed mechanism of chronic pain is dysregulation between the main
inhibitory (GABA) and excitatory (glutamate) neurometabolites of the central nervous system …

Purpose The Vespa package (Versatile Simulation, Pulses, and Analysis) is described and
demonstrated. It provides workflows for developing and optimizing linear combination …

Glutathione (GSH) is an important antioxidant implicated in several physiological functions,
including the oxidation− reduction reaction balance and brain antioxidant defense against …

Background Processing and quantitative analysis of magnetic resonance spectroscopy
(MRS) data are far from standardized and require interfacing with third-party software. Here …

γ-Aminobutyric acid (GABA) is the principal inhibitory neurotransmitter in the human brain
and can be measured with magnetic resonance spectroscopy (MRS). Conflicting accounts …

Spectral editing in in vivo 1H‐MRS provides an effective means to measure low‐
concentration metabolite signals that cannot be reliably measured by conventional MRS …

Accurate and reliable quantification of brain metabolites measured in vivo using 1 H
magnetic resonance spectroscopy (MRS) is a topic of continued interest. Aside from …

Purpose The purpose of this study is to present a cloud‐based spectral simulation tool
“MRSCloud,” which allows MRS users to simulate a vendor‐specific and sequence‐specific …

Edited MRS sequences are widely used for studying γ‐aminobutyric acid (GABA) in the
human brain. Several algorithms are available for modelling these data, deriving metabolite …

The aim of this guideline is to provide a series of evidence-based recommendations that
allow those new to using MEGA-PRESS to produce high-quality data for the measurement of …