Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …

Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …

The increasing prevalence of metabolic syndrome has become a serious public health
problem. Certain bacteria-derived metabolites play a key role in maintaining human health …

Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …

Mitochondria are highly dynamic organelles that serve as the primary cellular energy-
generating system. Apart from ATP production, they are essential for many biological …

Background Accumulating evidence indicates that high-fat diet (HFD) is a controllable risk
factor for osteoporosis, but the underlying mechanism remains to be elucidated. As a …

Obesity is often associated with the risk of chronic inflammation and other metabolic
diseases, such as diabetes, cardiovascular disease, and cancer. The composition and …

Abstract Aims Lactobacillus rhamnosus GG (LGG) is a probiotic with great promise in future
clinical application, which can significantly promote bone formation. However, the effect of …

The intricate interplay between gut microbiota and the host is pivotal in maintaining
homeostasis and health. Dietary tryptophan (TRP) metabolism initiates a cascade of …

Objectives The treatment of bone defects by stem cells (MSCs) has achieved limited success
over the recent few decades. The emergence of exosomes provides a new strategy for bone …