[HTML][HTML] Targeting gut microbiota and metabolism as the major probiotic mechanism-An evidence-based review
T Ma, X Shen, X Shi, HA Sakandar, K Quan, Y Li… - Trends in Food Science …, 2023 - Elsevier
Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …
health and disease. The gut microbiota is continuously reshaped by multiple environmental …
Biological effects of indole-3-propionic acid, a gut microbiota-derived metabolite, and its precursor tryptophan in mammals' health and disease
P Konopelski, I Mogilnicka - International journal of molecular sciences, 2022 - mdpi.com
Actions of symbiotic gut microbiota are in dynamic balance with the host's organism to
maintain homeostasis. Many different factors have an impact on this relationship, including …
maintain homeostasis. Many different factors have an impact on this relationship, including …
The mechanism underlying the influence of indole-3-propionic acid: A relevance to metabolic disorders
B Zhang, M Jiang, J Zhao, Y Song, W Du… - Frontiers in …, 2022 - frontiersin.org
The increasing prevalence of metabolic syndrome has become a serious public health
problem. Certain bacteria-derived metabolites play a key role in maintaining human health …
problem. Certain bacteria-derived metabolites play a key role in maintaining human health …
Cellular and molecular mechanisms associating obesity to bone loss
YS Forte, M Renovato-Martins, C Barja-Fidalgo - Cells, 2023 - mdpi.com
Obesity is an alarming disease that favors the upset of other illnesses and enhances
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …
mortality. It is spreading fast worldwide may affect more than 1 billion people by 2030. The …
The crosstalk between microbiome and mitochondrial homeostasis in neurodegeneration
Mitochondria are highly dynamic organelles that serve as the primary cellular energy-
generating system. Apart from ATP production, they are essential for many biological …
generating system. Apart from ATP production, they are essential for many biological …
Gut microbiota and serum metabolic signatures of high-Fat-Induced bone loss in mice
L Lu, M Tang, J Li, Y Xie, Y Li, J Xie, L Zhou… - Frontiers in cellular …, 2021 - frontiersin.org
Background Accumulating evidence indicates that high-fat diet (HFD) is a controllable risk
factor for osteoporosis, but the underlying mechanism remains to be elucidated. As a …
factor for osteoporosis, but the underlying mechanism remains to be elucidated. As a …
Gut and obesity/metabolic disease: focus on microbiota metabolites
K Lin, L Zhu, L Yang - MedComm, 2022 - Wiley Online Library
Obesity is often associated with the risk of chronic inflammation and other metabolic
diseases, such as diabetes, cardiovascular disease, and cancer. The composition and …
diseases, such as diabetes, cardiovascular disease, and cancer. The composition and …
Lactobacillus rhamnosus GG aggravates vascular calcification in chronic kidney disease: A potential role for extracellular vesicles
J Wei, Z Li, Y Fan, L Feng, X Zhong, W Li, T Guo… - Life Sciences, 2023 - Elsevier
Abstract Aims Lactobacillus rhamnosus GG (LGG) is a probiotic with great promise in future
clinical application, which can significantly promote bone formation. However, the effect of …
clinical application, which can significantly promote bone formation. However, the effect of …
[HTML][HTML] Microbiota-derived tryptophan metabolism: Impacts on health, aging, and disease
SK Gupta, S Vyavahare, ILD Blanes, F Berger… - Experimental …, 2023 - Elsevier
The intricate interplay between gut microbiota and the host is pivotal in maintaining
homeostasis and health. Dietary tryptophan (TRP) metabolism initiates a cascade of …
homeostasis and health. Dietary tryptophan (TRP) metabolism initiates a cascade of …
Exosome‐shuttled mitochondrial transcription factor A mRNA promotes the osteogenesis of dental pulp stem cells through mitochondrial oxidative phosphorylation …
J Guo, F Zhou, Z Liu, Y Cao, W Zhao, Z Zhang… - Cell …, 2022 - Wiley Online Library
Objectives The treatment of bone defects by stem cells (MSCs) has achieved limited success
over the recent few decades. The emergence of exosomes provides a new strategy for bone …
over the recent few decades. The emergence of exosomes provides a new strategy for bone …