Introduction: There is a paucity of data on incidence and mechanisms of long-term
gastrointestinal consequences after chemoradiotherapy for anal cancer. Most of the adverse …

Background Advanced pelvic radiotherapy techniques aim to reduce late bowel toxicity
which can severely impact the lives of pelvic cancer survivors. Although advanced …

Background and purpose Preoperative radiotherapy for rectal cancer has a detrimental
effect on long-term anorectal function and quality of life, additional to that observed after …

Purpose Changes in fraction size of external beam radiation therapy exert nonlinear effects
on subsequent toxicity. Commonly described by the linear-quadratic model, fraction size …

Fecal incontinence (FI) is a multifactorial disorder that imposes considerable social and
economic burdens. The aim of this article is to provide an overview of current and emerging …

Background Neoadjuvant radio-or chemoradiation (nIRT) therapy is the standard treatment
for loco-regional advanced rectal cancer patients of the lower or middle third. Currently …

During the past 30 years, radiation treatment techniques have significantly improved, from
conventional external-beam radiation therapy, to three-dimensional conformal radiation …

Background and purpose Concurrent chemoradiation (CCRT) is the standard treatment for
locally advanced anal canal carcinoma, although treatment-related side effects can affect …

Purpose To identify volume and dose predictors of paresthesia after irradiation of the
brachial plexus among women treated for breast cancer. Methods and Materials The women …

Background. The precise etiology of fecal incontinence (FI), which occurs frequently
following external beam radiotherapy (EBRT) for prostate carcinoma is unknown. It is …