[HTML][HTML] Müller cells and diabetic retinopathy
BA Coughlin, DJ Feenstra, S Mohr - Vision research, 2017 - Elsevier
Müller cells are one of the primary glial cell types found in the retina and play a significant
role in maintaining retinal function and health. Since Müller cells are the only cell type to …
role in maintaining retinal function and health. Since Müller cells are the only cell type to …
Causative links between protein aggregation and oxidative stress: a review
E Lévy, N El Banna, D Baïlle… - International journal of …, 2019 - mdpi.com
Compelling evidence supports a tight link between oxidative stress and protein aggregation
processes, which are noticeably involved in the development of proteinopathies, such as …
processes, which are noticeably involved in the development of proteinopathies, such as …
The diverse functions of GAPDH: views from different subcellular compartments
C Tristan, N Shahani, TW Sedlak, A Sawa - Cellular signalling, 2011 - Elsevier
Multiple roles for glyceraldehyde-3-phosphate dehydrogenase (GAPDH) have been recently
appreciated. In addition to the cytoplasm where the majority of GAPDH is located under the …
appreciated. In addition to the cytoplasm where the majority of GAPDH is located under the …
Molecular targets of oxidative stress
SV Avery - Biochemical Journal, 2011 - portlandpress.com
Aerobic life requires organisms to resist the damaging effects of ROS (reactive oxygen
species), particularly during stress. Extensive research has established a detailed picture of …
species), particularly during stress. Extensive research has established a detailed picture of …
Glycolytic metabolism, brain resilience, and Alzheimer's disease
X Zhang, N Alshakhshir, L Zhao - Frontiers in Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common form of age-related dementia. Despite
decades of research, the etiology and pathogenesis of AD are not well understood. Brain …
decades of research, the etiology and pathogenesis of AD are not well understood. Brain …
[PDF][PDF] Diverting glycolysis to combat oxidative stress
E Mullarky, LC Cantley - Innovative medicine: basic research and …, 2015 - library.oapen.org
Reactive oxygen species (ROS) are an intricate part of normal cellular physiology. In excess,
however, ROS can damage all three major classes of macromolecules and compromise cell …
however, ROS can damage all three major classes of macromolecules and compromise cell …
A proton relay enhances H2O2 sensitivity of GAPDH to facilitate metabolic adaptation
Abstract Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is sensitive to reversible
oxidative inactivation by hydrogen peroxide (H2O2). Here we show that H2O2 reactivity of …
oxidative inactivation by hydrogen peroxide (H2O2). Here we show that H2O2 reactivity of …
On the functional diversity of glyceraldehyde-3-phosphate dehydrogenase: biochemical mechanisms and regulatory control
MA Sirover - Biochimica et Biophysica Acta (BBA)-General Subjects, 2011 - Elsevier
Background New studies provide evidence that glyceraldehyde-3-phosphate
dehydrogenase (GAPDH) is not simply a classical glycolytic protein of little interest. Instead …
dehydrogenase (GAPDH) is not simply a classical glycolytic protein of little interest. Instead …
Role of free radical in atherosclerosis, diabetes and dyslipidaemia: larger‐than‐life
During the past few decades, there have been numerous studies related to free radical
chemistry. Free radicals including reactive oxygen species (ROS) and reactive nitrogen …
chemistry. Free radicals including reactive oxygen species (ROS) and reactive nitrogen …
Plant cytoplasmic GAPDH: redox post-translational modifications and moonlighting properties
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a ubiquitous enzyme involved in
glycolysis and shown, particularly in animal cells, to play additional roles in several …
glycolysis and shown, particularly in animal cells, to play additional roles in several …