Cataract and presbyopia are the leading cause of vision loss and impaired vision,
respectively, worldwide. Changes in lens biochemistry and physiology with age are …

Lens, an avascular tissue involved in light transmission, generates an internal
microcirculatory system to promote ion and fluid circulation, thus providing nutrients to …

Introduction Nodulin-26-like intrinsic proteins (NIPs) are integral membrane proteins
belonging to the aquaporin family, that facilitate the transport of neutral solutes across the …

Congenital cataracts are associated with gene mutations, yet the underlying mechanism
remains largely unknown. Here we reported an embryonic chick lens model that closely …

METHODS Two Chinese families with autosomal-dominant congenital cataract (ADCC)
were recruited and underwent comprehensive eye examinations. Gene panel next …

Amino acids are organic compounds that consist of alpha carbon in the center, hydrogen
(H), amino (-NH2), carboxyl (-COOH), and specific R (side chain) groups. One linear chain of …

Cataracts are mainly classified into three types: cortical cataracts, nuclear cataracts, and
posterior subcapsular cataracts. In addition, retrodots and waterclefts are cataract subtypes …