The CB2 receptor and its role as a regulator of inflammation
C Turcotte, MR Blanchet, M Laviolette… - Cellular and Molecular …, 2016 - Springer
The CB 2 receptor is the peripheral receptor for cannabinoids. It is mainly expressed in
immune tissues, highlighting the possibility that the endocannabinoid system has an …
immune tissues, highlighting the possibility that the endocannabinoid system has an …
From phytocannabinoids to cannabinoid receptors and endocannabinoids: pleiotropic physiological and pathological roles through complex pharmacology
A Ligresti, L De Petrocellis… - Physiological …, 2016 - journals.physiology.org
Apart from having been used and misused for at least four millennia for, among others,
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
recreational and medicinal purposes, the cannabis plant and its most peculiar chemical …
Cannabinoid CB2 receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice
Cannabinoid CB2 receptors (CB2Rs) have been recently reported to modulate brain
dopamine (DA)-related behaviors; however, the cellular mechanisms underlying these …
dopamine (DA)-related behaviors; however, the cellular mechanisms underlying these …
The endocannabinoid system as an emerging target of pharmacotherapy
The recent identification of cannabinoid receptors and their endogenous lipid ligands has
triggered an exponential growth of studies exploring the endocannabinoid system and its …
triggered an exponential growth of studies exploring the endocannabinoid system and its …
CB2: a cannabinoid receptor with an identity crisis
CB2 was first considered to be the 'peripheral cannabinoid receptor'. This title was bestowed
based on its abundant expression in the immune system and presumed absence from the …
based on its abundant expression in the immune system and presumed absence from the …
Cannabinoid CB2 receptors: immunohistochemical localization in rat brain
Brain expression of CB2 cannabinoid receptors has been much less well established and
characterized in comparison to the expression of brain CB1 receptors. Since CB2 receptors …
characterized in comparison to the expression of brain CB1 receptors. Since CB2 receptors …
Brain cannabinoid receptor 2: expression, function and modulation
Cannabis sativa (marijuana) is a fibrous flowering plant that produces an abundant variety of
molecules, some with psychoactive effects. At least 4% of the world's adult population uses …
molecules, some with psychoactive effects. At least 4% of the world's adult population uses …
Cannabinoid receptors 1 and 2 (CB1 and CB2), their distribution, ligands and functional involvement in nervous system structures—a short review
I Svíženská, P Dubový, A Šulcová - Pharmacology Biochemistry and …, 2008 - Elsevier
In the last 25 years data has grown exponentially dealing with the discovery of the
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …
endocannabinoid system consisting of specific cannabinoid receptors, their endogenous …
Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain
ES Onaivi, H Ishiguro, JP GONG, S Patel… - Annals of the New …, 2006 - Wiley Online Library
Two well‐characterized cannabinoid receptors (CBrs), CB1 and CB2, mediate the effects of
cannabinoids and marijuana use, with functional evidence for other CBrs. CB1 receptors are …
cannabinoids and marijuana use, with functional evidence for other CBrs. CB1 receptors are …
Differential expression of the CB2 cannabinoid receptor by rodent macrophages and macrophage-like cells in relation to cell activation
SJ Carlisle, F Marciano-Cabral, A Staab… - International …, 2002 - Elsevier
An in vitro model of multi-step activation, in which cells of macrophage lineage are driven
sequentially through inflammatory, primed, and fully activated states, was employed to …
sequentially through inflammatory, primed, and fully activated states, was employed to …