Mechanochemistry describes diverse phenomena in which mechanical load affects
chemical reactivity. The fuzziness of this definition means that it includes processes as …

Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …

Pharmaceutical drug therapy is often hindered by issues caused by poor drug selectivity,
including unwanted side effects and drug resistance. Spatial and temporal control over drug …

Polymers that release small molecules in response to mechanical force are promising
materials for a variety of applications ranging from sensing and catalysis to targeted drug …

Conspectus When one brings “polymeric materials” and “mechanical action” into the same
conversation, the topic of this discussion might naturally focus on everyday circumstances …

Catalysis is key to the effective and efficient transformation of readily available building
blocks into high value functional molecules and materials. For many years research in this …

The copper‐catalyzed azide/alkyne cycloaddition reaction (CuAAC) has emerged as the
most useful “click” chemistry. Polymer science has profited enormously from CuAAC by its …

Self‐healing is a natural process common to all living organisms which provides increased
longevity and the ability to adapt to changes in the environment. Inspired by this fitness …

Engineering applications of synthetic polymers are widespread due to their availability,
processability, low density, and diversity of mechanical properties (Figure 1a). Despite their …

Maleimide–thiol reactions are widely used to produce protein–polymer conjugates for
therapeutics. However, maleimide–thiol adducts are unstable in vivo or in the presence of …