The overactivation of glutamate receptors is a major cause of Ca2+ overload in cells,
potentially leading to cell damage and death. There is an abundance of agents and …

Neurotransmitter release and the role of adenosine in its regulation has been investigated
for more than twenty years, and it is now widely accepted that adenosine tonically inhibits …

The effects of selective adenosine receptor agonists [N6‐cyclopentyladenosine (CPA) and N‐
ethylcarboxamidoadenosine (NECA)] and antagonists {8‐cyclopentyl‐1, 3‐dipropylxanthine …

The effects of the adenosine A1 receptor agonist, N6-cyclopentyladenosine (CPA), on both
the increase in intracellular free Ca2+ concentration ([Ca2+] i) and on the release of …

Previous work showed the presence of adenosine receptors as well as adenosine uptake
and release mechanisms in developing chick retinal neurons in culture. In the present work …

We have previously demonstrated that oxypurinol (40 mg/kg ip), a xanthine oxidase
inhibitor, can reduce focal ischemic brain injury in the rat when applied pre-ischemically. By …

Spreading depression (SD) is known to be involved in the N-methyl-D-aspartate receptor-
mediated neuronal damage. In urethane-anesthetized rats, we examined the release of …

The influence of stimulus pulse duration on calcium mobilization triggering facilitation of
evoked [3H] acetylcholine ([3H] ACh) release by the A2A adenosine receptor agonist CGS …

We determined that activation of adenosine A1 receptors in striatal synaptosomes with 100
nM N6-cyclopentyladenosine (CPA) inhibited both the release of endogenous glutamate …

The protective effect of the propentofylline (HWA285) in a rat focal ischemia was
investigated. The preischemic administration of HWA285 (10 mg/kg ip) significantly reduced …