Application of microfluidic technologies to human assisted reproduction

GD Smith, S Takayama - MHR: Basic science of reproductive …, 2017 - academic.oup.com
Microfluidics can be considered both a science and a technology. It is defined as the study of
fluid behavior at a sub-microliter level and the investigation into its application to cell …

Emerging epigenomic landscapes of pancreatic cancer in the era of precision medicine

G Lomberk, N Dusetti, J Iovanna, R Urrutia - Nature communications, 2019 - nature.com
Genetic studies have advanced our understanding of pancreatic cancer at a mechanistic
and translational level. Genetic concepts and tools are increasingly starting to be applied to …

LoMA-B: a simple and versatile lab-on-a-chip system based on single-channel bisulfite conversion for DNA methylation analysis

J Yoon, MK Park, TY Lee, YJ Yoon, Y Shin - Lab on a Chip, 2015 - pubs.rsc.org
Miniaturized lab-on-a-chip (LOC) systems have been developed for genetic and epigenetic
analyses in clinical applications because of advantages such as reduced sample size and …

[HTML][HTML] Microfluidics for genome-wide studies involving next generation sequencing

S Ma, TW Murphy, C Lu - Biomicrofluidics, 2017 - pubs.aip.org
Next-generation sequencing (NGS) has revolutionized how molecular biology studies are
conducted. Its decreasing cost and increasing throughput permit profiling of genomic …

Fracture-based micro-and nanofabrication for biological applications

BC Kim, C Moraes, J Huang, MD Thouless… - Biomaterials …, 2014 - pubs.rsc.org
While fracture is generally considered to be undesirable in various manufacturing
processes, delicate control of fracture can be successfully implemented to generate …

Single molecule and single cell epigenomics

BR Hyun, JL McElwee, PD Soloway - Methods, 2015 - Elsevier
Dynamically regulated changes in chromatin states are vital for normal development and
can produce disease when they go awry. Accordingly, much effort has been devoted to …

Fracture‐based fabrication of normally closed, adjustable, and fully reversible microscale fluidic channels

BC Kim, C Moraes, J Huang, T Matsuoka, MD Thouless… - Small, 2014 - Wiley Online Library
Adjustable fluidic structures play an important role in microfluidic systems. Fracture of
multilayered materials under applied tension has been previously demonstrated as a …

Morphological plasticity of bacteria—Open questions

JP Shen, CF Chou - Biomicrofluidics, 2016 - pubs.aip.org
Morphological plasticity of bacteria is a cryptic phenomenon, by which bacteria acquire
adaptive benefits for coping with changing environments. Some environmental cues were …

Chromatin immunocapture devices and methods of use

R Bailey, T Joshua, T Ordog, JH Lee… - US Patent …, 2020 - Google Patents
2020-03-27 Assigned to THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS
reassignment THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS …

Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns

C Moraes, BC Kim, X Zhu, KL Mills, AR Dixon… - Lab on a Chip, 2014 - pubs.rsc.org
Culturing cells in three-dimensional (3D) environments has been shown to significantly
influence cell function, and may provide a more physiologically relevant environment within …