Selenium nanoparticles and quercetin suppress thioacetamide‐induced hepatocellular carcinoma in rats: Attenuation of inflammation involvement
AA Mohamed, RA Zaghloul… - … of Biochemical and …, 2022 - Wiley Online Library
The current study investigates the anti‐inflammatory and hepatoprotective effects of
selenium (Se) formulated as nanoparticles (SeNPs) and in combination with quercetin …
selenium (Se) formulated as nanoparticles (SeNPs) and in combination with quercetin …
Integrated bioinformatics analysis to identify alternative therapeutic targets for Alzheimer's disease: insights from a synaptic machinery perspective
H Ceylan - Journal of Molecular Neuroscience, 2022 - Springer
Abstract Alzheimer's disease (AD), the most common type of dementia, is a serious
neurodegenerative disease that has no cure yet, but whose symptoms can be alleviated with …
neurodegenerative disease that has no cure yet, but whose symptoms can be alleviated with …
Investigation of the multi-targeted protection potential of tannic acid against doxorubicin-induced kidney damage in rats
EN Yesilkent, H Ceylan - Chemico-biological interactions, 2022 - Elsevier
Doxorubicin (DOX) is an antitumor drug that is powerful but can cause worse outcomes,
including nephrotoxicity, and therefore has limited clinical use. Therefore, it is necessary to …
including nephrotoxicity, and therefore has limited clinical use. Therefore, it is necessary to …
Bioinformatics‐based identification of hepatocellular carcinoma‐associated hub genes and assessment of the restorative effect of tannic acid in rat liver exposed to …
H Tosun, H Karadas, H Ceylan - Cancer Medicine, 2024 - Wiley Online Library
Background Hepatocellular carcinoma (HCC) is the most common type of primary liver
cancer, occurring mostly in individuals with chronic liver disease, but biomarkers for …
cancer, occurring mostly in individuals with chronic liver disease, but biomarkers for …
Involvement of the circular RNA/microRNA/glucose-6-phosphate dehydrogenase axis in the pathological mechanism of hepatocellular carcinoma
Y Wang, XY Zhou, XY Lu, KD Chen, HP Yao - Hepatobiliary & Pancreatic …, 2021 - Elsevier
Hepatocellular carcinoma (HCC) is the third most common cause of cancer-related death
worldwide with high mortality. The incidence of HCC is increasing in China. Abnormal …
worldwide with high mortality. The incidence of HCC is increasing in China. Abnormal …
The hepatic antioxidant system damage induced with the cafeteria (CAF) diet is largely counteracted using SCD probiotics during development of male Wistar rats
N Aba, EF Koçpınar, T Ceylani - Nutrients, 2023 - mdpi.com
The cafeteria (CAF) diet, reflective of predominant Western dietary behaviors, is implicated
in hastening weight gain, subsequently resulting in health complications such as obesity …
in hastening weight gain, subsequently resulting in health complications such as obesity …
Association of glucose-6-phosphate dehydrogenase (G6PD) expression and obesity: A systematized review
EG Fojas, N Lessan, MA Chiong, R Naemi - Obesity Medicine, 2024 - Elsevier
Several studies have associated glucose-6-phosphate dehydrogenase (G6PD)
overexpression with obesity due to its roles in proinflammatory signalling. However, a …
overexpression with obesity due to its roles in proinflammatory signalling. However, a …
Identification and validation of core genes as promising diagnostic signature in hepatocellular carcinoma based on integrated bioinformatics approach
The primary objective of this investigation was to determine the hub genes of hepatocellular
carcinoma (HCC) through an in silico approach. In the current context of the increased …
carcinoma (HCC) through an in silico approach. In the current context of the increased …
Neuroprotective potential of tannic acid against neurotoxic outputs of monosodium glutamate in rat cerebral cortex
MS Karagac, H Ceylan - Neurotoxicity Research, 2023 - Springer
Glutamate in monosodium glutamate (MSG), which is widely used in the food industry, has
an important role in major brain functions such as memory, learning, synapse formation, and …
an important role in major brain functions such as memory, learning, synapse formation, and …
Applications of bioinformatics tools in medicinal biology and biotechnology
H Shah, V Chavda, MM Soniwala - Bioinformatics Tools for …, 2023 - Wiley Online Library
Development of modern medicine necessitates the collection, integration and interpretation
of molecular, genomic, and cellular data, together with clinical data. Hence, it produces a …
of molecular, genomic, and cellular data, together with clinical data. Hence, it produces a …