Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …

Since their discovery in the early 20th century, antibiotics have been used as the primary
weapon against bacterial infections. Due to their prophylactic effect, they are also used as …

Organic fluorine compounds have had a profound impact on the development of bioactives
for the modern pharmaceuticals market. It is estimated that up to 20% of pharmaceuticals …

The in-situ generation of nanostructured materials on the metal-based carriers nickel foam
(NF) is a novel technique for water remediation materials. In this study, Mn 2 O 3/MnCo 2 O 4 …

BACKGROUND: Premarketing trials showed the fluoroquinolone agents to have a favorable
side-effect profile, with treatment-related adverse events comprising gastrointestinal, central …

Many attempts have been made to prepare analogs of 4‐quinolone antibacterial agents
bearing novel ring systems, which might retain the favorable properties of these widely used …

The aim of this study was to compare the in vitro susceptibility of Klebsiella pneumoniae,
Pseudomonas aeruginosa and Stenotrophomonas maltophilia to three fluoroquinolones …

Levofloxacin (LV) is a hydrophilic broad-spectrum antibiotic commonly used in pulmonary
treatment against recurrent infections of Pseudomonas aeruginosa, and particularly in cystic …

Extensive pharmacologic and clinical development of quinolone antimicrobial agents has
resulted in improved antimicrobial activity, pharmacokinetic features, toxicity, and drug‐drug …

A number of new fluoroquinolone antibacterials have been released for clinical use in recent
years. These new agents exhibit enhanced activity against Gram-positive organisms while …