The integral role of RNA in stress granule formation and function
D Campos-Melo, ZCE Hawley… - Frontiers in Cell and …, 2021 - frontiersin.org
Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …
(RNP) assemblies whose primary function is to promote cell survival by condensing …
Mechanisms and regulation of RNA condensation in RNP granule formation
Ribonucleoprotein (RNP) granules are RNA–protein assemblies that are involved in
multiple aspects of RNA metabolism and are linked to memory, development, and disease …
multiple aspects of RNA metabolism and are linked to memory, development, and disease …
Promiscuous interactions and protein disaggregases determine the material state of stress-inducible RNP granules
RNA-protein (RNP) granules have been proposed to assemble by forming solid RNA/protein
aggregates or through phase separation into a liquid RNA/protein phase. Which model …
aggregates or through phase separation into a liquid RNA/protein phase. Which model …
Stress granules and cell signaling: more than just a passing phase?
N Kedersha, P Ivanov, P Anderson - Trends in biochemical sciences, 2013 - cell.com
Stress granules (SGs) contain translationally-stalled mRNAs, associated preinitiation factors,
and specific RNA-binding proteins. In addition, many signaling proteins are recruited to SGs …
and specific RNA-binding proteins. In addition, many signaling proteins are recruited to SGs …
Stress granules: the Tao of RNA triage
P Anderson, N Kedersha - Trends in biochemical sciences, 2008 - cell.com
Cytoplasmic RNA structures such as stress granules (SGs) and processing bodies (PBs) are
functional byproducts of mRNA metabolism, sharing substrate mRNA, dynamic properties …
functional byproducts of mRNA metabolism, sharing substrate mRNA, dynamic properties …
Post-transcriptional regulatory functions of mammalian pumilio proteins
AC Goldstrohm, TMT Hall, KM McKenney - TRENDS in Genetics, 2018 - cell.com
Mammalian Pumilio proteins, PUM1 and PUM2, are members of the PUF family of sequence-
specific RNA-binding proteins. In this review, we explore their mechanisms, regulatory …
specific RNA-binding proteins. In this review, we explore their mechanisms, regulatory …
[HTML][HTML] microRNAs at the synapse
G Schratt - Nature Reviews Neuroscience, 2009 - nature.com
MicroRNAs (miRNAs) are emerging as key modulators of post-transcriptional gene
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …
regulation in a plethora of tissues, including the nervous system. Recent evidence points to …
A conserved abundant cytoplasmic long noncoding RNA modulates repression by Pumilio proteins in human cells
A Tichon, N Gil, Y Lubelsky, T Havkin Solomon… - Nature …, 2016 - nature.com
Thousands of long noncoding RNA (lncRNA) genes are encoded in the human genome,
and hundreds of them are evolutionarily conserved, but their functions and modes of action …
and hundreds of them are evolutionarily conserved, but their functions and modes of action …
[HTML][HTML] Neuronal RNA granules: movers and makers
MA Kiebler, GJ Bassell - Neuron, 2006 - cell.com
RNA localization contributes to cell polarity and synaptic plasticity. Evidence will be
discussed that RNA transport and local translation in neurons may be more intimately linked …
discussed that RNA transport and local translation in neurons may be more intimately linked …
[HTML][HTML] Dendritic mRNA: transport, translation and function
CR Bramham, DG Wells - Nature Reviews Neuroscience, 2007 - nature.com
Many cellular functions require the synthesis of a specific protein or functional cohort of
proteins at a specific time and place in the cell. Local protein synthesis in neuronal dendrites …
proteins at a specific time and place in the cell. Local protein synthesis in neuronal dendrites …